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This study evaluates treatment outcomes from a clinical cohort with task-sharing between a clinical nurse practitioner and a medical officer. The researchers examined opportunities to increase treatment rates for multidrug-resistant tuberculosis in South Africa.     Read more   Climate Change   Health Impact of Climate Change in Older People: An Integrative Review and Implications for Nursing by Erwin William A. Leyva*, Adam Beaman, and Patricia Davidson in the Journal of Nursing Scholarship Older people account for the highest proportion of mortality from extreme weather events associated with climate change. This article describes the health impacts of climate change on that population.     Read more   ...
Source: Johns Hopkins University and Health Systems Archive - Category: Nursing Source Type: news

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ConclusionWe determine that VSMCs promote recovery of infarcted cardiomyocyte through secretion of bFGF, which then activating PI3K/Akt pathway to inhibit apoptosis and autophagy. These findings provide more insights into the molecular mechanism underlying VSMCs contributing to recovery of myocardial I/R and facilitate developing therapeutical strategies for treating heart diseases.Graphical abstract
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
In conclusion, Se-NPs could be a potent maternal prophylactic agent against the reduced total serum testosterone level and oxidative damage of Leydig cells induced by DBP via reducing the lipid peroxidation (LPO) and enhancing the antioxidant state in pre-pubertal male rat offspring.Graphical abstract
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Publication date: November 2018Source: Biomedicine &Pharmacotherapy, Volume 107Author(s): Hadi Naderi, Gholamreza Pourmand, Sanaz Dehghani, Hassan Nikoueinejad, Mohammad Jafari, Nader TajikAbstractMaintaining the balance between over- and under-immunosuppression has a critical role for successful immunosuppressive therapy after renal transplantation. We studied the predictive value of our functional immune assay, which works based on adenosine triphosphate (ATP) levels, in determining risk of infection and rejection among renal transplant recipients (RTRs). A total of 65 RTRs with less than 1 month (RTRL1) and 48 RTRs ...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
CONCLUSIONS: Weight discrimination has been associated consistently with poor outcomes in adulthood. The present research indicates these associations extend to adolescence and an extremely consequential outcome: the social experience of weight increases risk of intentional self-harm and suicidal behavior. PMID: 30226995 [PubMed - as supplied by publisher]
Source: Childhood Obesity - Category: Eating Disorders & Weight Management Tags: Child Obes Source Type: research
CONCLUSIONS: Findings document associations between childhood weight status and subsequent onset of first sexual intercourse, especially among Hispanic females and males and white males. Together, results highlight respondent sex and race/ethnicity as potential moderators and also unique risk for Hispanic females who were overweight as children, and who may benefit from early screening and education to delay sexual initiation to reduce risk of early unplanned pregnancy and sexually transmitted infections. PMID: 30226993 [PubMed - as supplied by publisher]
Source: Childhood Obesity - Category: Eating Disorders & Weight Management Tags: Child Obes Source Type: research
Riccardo Arrigucci, Karim Lakehal, Pooja Vir, Deborah Handler, Amy L. Davidow, Rosa Herrera, Julia Dolores Estrada-Guzm án, Yuri Bushkin, Sanjay Tyagi, Alfred A. Lardizabal, Maria Laura Gennaro
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Robert L. Hunter
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Scientists are concerned by nitrogen dioxide and sooty smog belched out by old diesel cars in the UK. The findings provide the strongest evidence so far that toxic fumes are linked to Alzheimer ’s.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
VITAMIN B12 deficiency symptoms can cause anaemia and lead to a number of complications, including heart failure. For this reason, noticing the first signs is very important - one sign can be found in your legs and feet.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Authors: Laflamme N, Préfontaine P, Lampron A, Rivest S Abstract Bone marrow transplantation is the standard of care for a host of diseases such as leukemia and multiple myeloma, as well as genetically inherited metabolic diseases affecting the central nervous system. In mouse models, bone marrow transplantation has proven a valuable tool for understanding the hematopoietic system and the homing of hematopoietic cells to their target organs. Many techniques have been developed to create chimeric mice, animals with a hematopoietic system derived from a genetic background that differs from the rest of the body...
Source: Current Protocols in Immunology - Category: Allergy & Immunology Tags: Curr Protoc Immunol Source Type: research
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