Spurious Hyperchloremia in the Presence of Elevated Plasma Salicylate: A Cohort Study

Conclusion: Circulating levels of salicylate can interfere with chloride measured by using routine techniques, resulting in spurious hyperchloremia outcomes and erroneous AG values. In patients with acute metabolic acidosis and abnormally reduced or negative AG, salicylate interference with chloride measurement should be suspected.Nephron
Source: Nephron - Category: Urology & Nephrology Source Type: research