Kenya:Help for Couples in Nairobi With Infertility

[MumsVillage] Difficulty in conceiving is common, experienced by one in every six couples. This frequency increases with age, especially after the age of 35.
Source: AllAfrica News: Pregnancy and Childbirth - Category: OBGYN Source Type: news

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Capsid protein Vp1 from chlamydiaphage φCPG1 effectively alleviates cytotoxicity induced by Chlamydia trachomatis. Exp Ther Med. 2018 Oct;16(4):3286-3292 Authors: Ren J, Guo Y, Shao L, Liu Y, Liu Q Abstract Chlamydia trachomatis is the leading cause of sexually transmitted bacterial infections. C. trachomatis genital infection may lead to pelvic inflammatory disease, ectopic pregnancy and tubal infertility, which are major public health problems. However, the pathogenic mechanisms of this bacterium remain unclear, and the efficacy of clinical therapeutics is unsatisfactory. In the current study, wh...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Condition:   Infertility Interventions:   Drug: Metformin;   Drug: Placebo;   Drug: Clomiphene Citrate Sponsor:   Elham Raafat Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: November 2018Source: Biomedicine &Pharmacotherapy, Volume 107Author(s): An Wei, Hao Feng, Xiao-Min Jia, Hua Tang, Yang-Ying Liao, Bi-Rong LiAbstractAs a common cause of infertility, pelvic inflammatory disease (PID) is characterized by chronic pain, ectopic pregnancy as well as inflammation and infection of the female upper genital tract. Ozone water, also known as O3, has been previously reported to be a distinctly effective agent in treating inflammation. During the present study, we asserted the hypothesis that O3 could be applied by pelvic inflammation and works to regulate the expression of infla...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Authors: Han Y, Luo H, Zhang Y Abstract This retrospective cohort study aimed to analyse the risk of congenital anomalies (CAs) in infants conceived by infertile women through assisted reproductive technology (ART). A total of 9,013 clinical pregnancy cycles resulting in 9,101 live births between 2004 and 2014 were analysed. Congenital anomalies were evaluated and compared with spontaneous pregnancies in infertile women. A total of 9,101 infants were born following ART. Three subgroups were established: In vitro fertilisation fresh embryo transfer (IVF-ET), n=2,919, intracytoplasmic sperm injection fresh embryo tra...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Publication date: Available online 13 September 2018Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Tabibnejad N., Soleimani M., A. AflatoonianAbstractObjectivesOocyte parameters as well as embryo developmental kinetics can be applied as non-invasive predictors for selection of viable embryos and clinical outcomes. Time-lapse morphokinetic events in conjunction with zona pellucida birefringence (ZPB) and meiotic spindle visualization (MSV) have been evaluated for predicting pregnancy outcome.Study designWe assessed a total of 547 embryos from 100 intra cytoplasmic sperm injection c...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Sometimes the medical decisions which infertile patients need to make can be very simple , because there really aren't too many options. Thus if your tubes are blocked , your only treatment option is IVF , so your only decision is which IVF clinic to select.On the other hand, you may find that you have lots of treatment options , and you then need to decide what's right for you. Thus, if you are older, you may be able to get pregnant with your own eggs, but you know that your chances of getting pregnant with donor eggs are much higher .You are not sure which is the right decision. Should you go for donor eggs, because it h...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
Abstract BACKGROUND: Letrozole is widely employed as ovulation induction agent in women with PCOS, but its use in mild stimulation (MS) protocols for IVF is limited. Aim of the present study was to evaluate the feasibility of a MS protocol with letrozole plus hMG in non-obese PCOS women undergoing IVF after a metformin pre-treatment. METHODS: We retrospectively evaluated the data of 125 non-obese PCOS undergoing MS with letrozole plus hMG, 150 IU as starting dose, (group 1, N = 80) compared to those undergoing a conventional IVF stimulation protocols (CS) (group 2, N = 45) pri...
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Tags: Reprod Biol Endocrinol Source Type: research
Publication date: Available online 13 September 2018Source: Best Practice &Research Clinical Endocrinology &MetabolismAuthor(s): Jorge Rodriguez-Purata, Nikolaos P. PolyzosAbstractControlled ovarian hyperstimulation (COH) is a key part of assisted reproductive technologies (ART) that resulted in a substantial increase in pregnancy rates from in vitro fertilization (IVF). However, in spite of the clear benefit of COH on an increase in the number of follicles and the number of oocytes retrieved, allowing for extended embryo culture and enabling the selection of the best quality embryo for transfer, several reports ha...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - Category: Endocrinology Source Type: research
Authors: Kim GY Abstract In an age when a small quantity of sperm can lead to pregnancy through in vitro fertilization or intracytoplasmic sperm injection, selecting healthy sperm is important. Sperm DNA fragmentation (SDF) is known to be higher in infertile men. Terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick end labeling (TUNEL) and the alkaline comet test are SDF tests that directly measure DNA damage and have shown closer correlations with assisted reproduction results than indirect tools such as the sperm chromatin structure assay or the sperm chromatic dispersion test. It is diff...
Source: Clinical and Experimental Reproductive Medicine - Category: Reproduction Medicine Tags: Clin Exp Reprod Med Source Type: research
Controlled ovarian hyperstimulation (COH) is a key part of assisted reproductive technologies (ART) that resulted in a substantial increase in pregnancy rates from in vitro fertilization (IVF). However, in spite of the clear benefit of COH on an increase in the number of follicles and the number of oocytes retrieved, allowing for extended embryo culture and enabling the selection of the best quality embryo for transfer, several reports has shown that the supraphysiological hormonal levels may indeed have a detrimental effect on the endometrial level.
Source: Best Practice and Research. Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Source Type: research
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