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Sinusitis caused by Exserohilum rostratum after cord blood transplantation for myelodysplastic syndrome: A case report and literature review

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Source: Transplant Infectious Disease - Category: Transplant Surgery Authors: Tags: Case Report Source Type: research

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CONCLUSIONS: Budesonide effectively mitigated LIRI and ameliorated the lung function by attenuating oxidative stress and inflammation following syngeneic lung transplantation. PMID: 29236548 [PubMed - as supplied by publisher]
Source: Experimental Lung Research - Category: Respiratory Medicine Tags: Exp Lung Res Source Type: research
Urinary markers of kidney fibrosis may provide important clues into the cardiovascular risk in kidney transplant recipients.American Journal of Transplantation
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Transplantation Journal Article Source Type: news
The population of stem cells that supports muscle tissue is one of the better studied classes of such cell. Stem cells enable tissue maintenance and regeneration by delivering a supply of new daughter somatic cells that can multiple to make up losses, and through signaling that alters cell behavior. This activity declines with advancing age, however, with stem cells spending ever more of their time in a quiescent state. This is thought to be a response to rising levels of cell damage and tissue dysfunction, behavior that evolved because it serves to reduce the risk of cancer over a period in which our ancestors were under ...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
Publication date: Available online 14 December 2017 Source:Trends in Genetics Author(s): Elizabeth S. Egan Severe malaria is caused by the Apicomplexan parasite Plasmodium falciparum, and results in significant global morbidity and mortality, particularly among young children and pregnant women. P. falciparum exclusively infects human erythrocytes during clinical illness, and several natural erythrocyte polymorphisms are protective against severe malaria. Since erythrocytes are enucleated and lack DNA, genetic approaches to understand erythrocyte determinants of malaria infection have historically been limited. This revie...
Source: Trends in Genetics - Category: Genetics & Stem Cells Source Type: research
Publication date: Available online 14 December 2017 Source:Fungal Biology Author(s): Guilherme T.P. Brancini, Ludmilla Tonani, Drauzio E.N. Rangel, Donald W. Roberts, Gilberto U.L. Braga Species of the Metarhizium anisopliae complex are globally ubiquitous soil-inhabiting and predominantly insect-pathogenic fungi. The Metarhizium genus contains species ranging from specialists, such as Metarhizium acridum that only infects acridids, to generalists, such as Metarhizium anisopliae, Metarhizium brunneum, and Metarhizium robertsii that cause disease in a broad range of insects and can also colonize plant roots. There is littl...
Source: Fungal Biology - Category: Biology Source Type: research
Mismatched unrelated donor allogeneic stem cell transplant for high risk haematological malignancy: A single centre experience, Published online: 15 December 2017; doi:10.1038/s41408-017-0012-0Mismatched unrelated donor allogeneic stem cell transplant for high risk haematological malignancy: A single centre experience
Source: Blood Cancer Journal - Category: Hematology Authors: Source Type: research
Anemia in myelofibrosis—prevalence, the U2AF1 connection, new treatmentsAnemia in myelofibrosis—prevalence, the U2AF1 connection, new treatments, Published online: 15 December 2017; doi:10.1038/s41408-017-0032-9Anemia in myelofibrosis—prevalence, the U2AF1 connection, new treatments
Source: Blood Cancer Journal - Category: Hematology Authors: Source Type: research
B-cell differentiation is one of the most recognized examples of the progressive lineage commitment that is distinctive for stem cell systems. However, the characteristics of the stage just before a cell becomes restricted to the B-cell lineage are less understood. Using single-cell RNA sequencing technology, Rolink and colleagues are able to define the cellular heterogeneity at this step and challenge our understanding of developmental trajectories in early B-lymphoid development (Alberti-Servera et al, 2017).
Source: EMBO Journal - Category: Molecular Biology Authors: Tags: Chromatin, Epigenetics, Genomics & Functional Genomics, Development & Differentiation, Immunology News [amp ] Views Source Type: research
Cells employ potentially mutagenic DNA repair mechanisms to avoid the detrimental effects of chromosome breaks on cell survival. While classical non-homologous end-joining (cNHEJ) is largely error-free, alternative end-joining pathways have been described that are intrinsically mutagenic. Which end-joining mechanisms operate in germ and embryonic cells and thus contribute to heritable mutations found in congenital diseases is, however, still largely elusive. Here, we determined the genetic requirements for the repair of CRISPR/Cas9-induced chromosomal breaks of different configurations, and establish the mutational consequ...
Source: EMBO Journal - Category: Molecular Biology Authors: Tags: DNA Replication, Repair & Recombination, Stem Cells Articles Source Type: research
This study provides a mechanistic understanding of how MCPH1 controls neural stem cell fate and brain development.
Source: EMBO Journal - Category: Molecular Biology Authors: Tags: Cell Cycle, Neuroscience Articles Source Type: research
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