Sod2 gene polymorphism may modulate some biochemical responses to a 12-week swimming training.

In conclusion, 12-week swimming training induces changes in oxidative stress and muscle damage parameters, as well as in lipid profile. These changes seem to be associated with the presence of SOD2 Val16Ala polymorphism. Presence of Ala allele, especially as homozygote, is associated with some beneficial post-training changes, such as a decrease in lipid peroxidation and less pronounced muscle damage. In turn, the influence of SOD2 Val16Ala polymorphism on the changes in lipid profile in response to chronic swimming training should be verified in further study. PMID: 29109056 [PubMed - as supplied by publisher]
Source: Free Radical Biology and Medicine - Category: Biology Authors: Tags: Free Radic Biol Med Source Type: research