Biochemical profiles of hydatid cystic fluid from infected dromedary camels, cattle and goats in Oman

This study was performed to evaluate the electrolytes and biochemical profiles in hydatid cyst fluid (HCF) collected from 60 slaughtered animals (dromedary camels, goats and cattle) in Oman. The Beckman Coulter Chemistry Analyser was used to analyse the HCF aspirated from 30 fertile and 30 sterile cysts collected from livers and lungs. The results revealed that the means of sodium, calcium, glucose, magnesium, creatinine and total protein in dromedary camels, cattle and goats varied significantly (p 
Source: Comparative Clinical Pathology - Category: Pathology Source Type: research

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Homology modeling and molecular dynamics dimulation study of β carbonic anhydrase of Ascaris lumbricoides. Bioinformation. 2019;15(8):572-578 Authors: Yadav M, Khandelwal S Abstract Ascaris lumbricoides is the prevalent parasite causing ascariasis by infecting the human alimentary tract. This is common in the jejunum of small intestine. Therefore, it is of interest to describe the target protein β Carbonic Anhydrase involved in Ascariasis. Carbonic anhydrase (CAs, the metallo enzymes) is encoded by six evolutionary divergent gene families α, β,γ, δ, ζ, and η, ...
Source: Bioinformation - Category: Bioinformatics Authors: Tags: Bioinformation Source Type: research
Publication date: Available online 14 November 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Lorena Porte, Thomas Weitzel
Source: The Brazilian Journal of Infectious Diseases - Category: Infectious Diseases Source Type: research
This article aims to describe the current seek medical status of chronic liver diseases and discuss a stage-based consulting medical model for chronic liver diseases in China mainland, which would contribute to make rational use of limited medical resources and help to address National Health China 2030 strategy initiated by the Chinese government. PMID: 31711913 [PubMed - as supplied by publisher]
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
Abstract Sri Lanka reports a large epidemic of cutaneous leishmaniasis (CL) caused by an atypical L. donovani while regional leishmaniasis elimination drive aims at achieving its targets in 2020. Visceralization, mucotrophism, and CL associated poor treatment response were recently reported. Long-term clinico-epidemiological trends (2001-2013) in this focus were examined for the first time. Both constant and changing features were observed. Sociodemographic patient characteristics that differ significantly from those of country profile, microchanges within CL profile, spatial expansion, constant biannual seasonal ...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
(University of Bern) An international scientific consortium led by the cell biologists Volker Heussler from the University of Bern and Oliver Billker from the Ume å University in Sweden has for the first time systematically investigated the genome of the malaria parasite Plasmodium throughout its life cycle in a large-scale experiment. The researchers were able to identify hundreds of targets that are urgently needed in drug and vaccine development to eradicate the disease.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
Publication date: Available online 13 November 2019Source: Saudi Pharmaceutical JournalAuthor(s): María Esperanza Adrover, Marisa Pedernera, Magali Bonne, Bénédicte Lebeau, Verónica Bucalá, Loreana GalloAbstractAlbendazole (ABZ, anti-parasitic active pharmaceutical ingredient) is a crystalline low water-soluble drug, thus the dissolution rate in gastrointestinal fluids is limited. Consequently, the improvement of the water solubility and dissolution rate of ABZ implies a great challenge for a more efficient treatment of hydatidosis. In this context, SBA-15 and SBA-16 ordered mesoporous si...
Source: Saudi Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
AbstractHypericum erectum is an important ethnobotanical medicine in East Asian tradition. To explore the anti-parasitic potential ofH. erectum, inhibitory effects on the growth of intracellular parasiteToxoplasma and on the encystation of intestinal parasiteEntamoeba were examined. The constituents inH. erectum alcoholic extracts and fractions separated by solvent-partitioning were analysed by high resolution LC –MS.Toxoplasma gondii growth inhibition assay was performed using GFP-labelledT. gondii strain PTG-GFP by measuring the fluorescence intensity. Anti-Toxoplasma drug pyrimethamine was used as a positive contr...
Source: Journal of Natural Medicines - Category: Drugs & Pharmacology Source Type: research
Publication date: April 2020Source: Parasitology International, Volume 75Author(s): Hideyuki Iriko, Tomoko Ishino, Mayumi Tachibana, Ayaka Omoda, Motomi Torii, Takafumi TsuboiAbstractPlasmodium falciparum proteins involved in vascular endothelial cell adherence are transported to the surface of infected erythrocytes. These proteins are exported through parasite-derived membrane structures within the erythrocyte cytoplasm called Maurer's clefts. Skeleton binding protein 1 (SBP1) is localized in the Maurer's clefts and plays an important role in transporting molecules to the surface of infected erythrocytes. Details of the t...
Source: Parasitology International - Category: Parasitology Source Type: research
Publication date: Available online 12 November 2019Source: Veterinary ParasitologyAuthor(s): Pornanan Kueakhai, Kulathida Chaithirayanon, Athit Chaiwichien, Tepparit Samrit, Supawadee Osotprasit, Phawiya Suksomboon, Wipaphorn Jaikua, Prasert Sobhon, Narin ChangklungmoaAbstractGlutathione peroxidases (GPx), major antioxidant enzymes, secreted by Fasciola spp., are important for the parasite evasion and protection against the host’s immune responses. In the present study, a monoclonal antibody (MoAb) against recombinant F. gigantica glutathione peroxidase (rFgGPx) was produced by hybridoma technique using spleen cells ...
Source: Veterinary Parasitology - Category: Veterinary Research Source Type: research
Publication date: Available online 12 November 2019Source: MicronAuthor(s): Andrezza Raposo Borges de Melo, Taciana Mirely Maciel Higino, Aline Dulce Pitt da Rocha Oliveira, Adriana Fontes, Diego César Nunes da Silva, Maria Carolina Accioly Brelaz de Castro, José Arimatéia Dantas Lopes, Regina Celia Bressan Queiroz de FigueiredoAbstractChagas disease, caused by the protozoan Trypanosoma cruzi, is considered a public health problem. The current chemotherapy for this illness causes serious side effects and its use in the chronic phase of the disease is still controversial. In this sense, the investigatio...
Source: Micron - Category: Biology Source Type: research
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