Epitope Preservation Methods for Tissue Microarrays: Longitudinal Prospective Study.

Conclusions: For precut slides, there is a time, storage condition, and antibody-dependent loss of immunoreactivity that could compromise analysis of prognostic, predictive, and diagnostic markers. Our findings support previous recommendations and suggest that the best storage conditions are at -20°C, without paraffin coating or vacuum sealing.
PMID: 29106459 [PubMed - in process]

Source: American Journal of Clinical Pathology - November 2, 2017 Category: Pathology Authors: Andeen NK, Bowman R, Baullinger T, Brooks JM, Tretiakova MS Tags: Am J Clin Pathol Source Type: research