An ancestry ‐based approach for detecting interactions

ConclusionWe show that genetic ancestry can be a useful proxy for unknown and unmeasured covariates in the search for interaction effects. These results have important implications for our understanding of the genetic architecture of complex traits.

Source: Genetic Epidemiology - November 1, 2017 Category: Epidemiology Authors: Danny S. Park, Itamar Eskin, Eun Yong Kang, Eric R. Gamazon, Celeste Eng, Christopher R. Gignoux, Joshua M. Galanter, Esteban Burchard, Chun J. Ye, Hugues Aschard, Eleazar Eskin, Eran Halperin, Noah Zaitlen Tags: RESEARCH ARTICLE Source Type: research