Frontline therapy of acute promyelocytic leukemia: Randomized comparison of ATRA and intensified chemotherapy versus ATRA and anthracyclines

ConclusionsThe small number of patients limits the reliability of conclusions. With these restrictions, the outcomes of both approaches were similar and show the limitations of ATRA and chemotherapy. The HD ara‐C containing regimen was associated with a lower relapse rate in high risk APL.This article is protected by copyright. All rights reserved.

Source: European Journal of Haematology - November 7, 2017 Category: Hematology Authors: Eva Lengfelder, Dennis G örlich, Daniel Nowak, Karsten Spiekermann, Claudia Haferlach, Utz Krug, Karl‐Anton Kreuzer, Jan Braess, Christoph Schliemann, Hans‐Walter Lindemann, Heinz A. Horst, Xaver Schiel, Michael Flasshove, Anna Hecht, Susanne Schnitt Tags: Original Article Source Type: research