Middle East respiratory syndrome coronavirus (MERS-CoV) – Saudi Arabia
Update on MERS CoV in Saudi Arabia, 7 November 2017
Abstract This nationwide, prospective cohort study evaluated pulmonary function and radiological sequelae according to infection severity in 73 survivors from the 2015 Middle East respiratory syndrome (MERS) outbreak in Korea. Patients with severe pneumonia in MERS-coronavirus infection had more impaired pulmonary function than those with no or mild pneumonia at the 1-year follow-up, which was compatible with the radiological sequelae. Severe pneumonia significantly impairs pulmonary function and makes long radiological sequelae in MERS. PMID: 29892209 [PubMed - in process]
Young Go The Middle East respiratory syndrome-coronavirus (MERS-CoV), first identified in Saudi Arabia, is an emerging zoonotic pathogen that causes severe acute respiratory illness in humans with a high fatality rate. Since its emergence, MERS-CoV continues to spread to countries outside of the Arabian Peninsula and gives rise to sporadic human infections following the entry of infected individuals to other countries, which can precipitate outbreaks similar to the one that occurred in South Korea in 2015. Current therapeutics against MERS-CoV infection have primarily been adapted from previous drugs used for the trea...
(KDKA/CBS Local) – Researchers say they have identified a new pig virus that could be a threat to humans. The virus was found to easily make its way into laboratory-cultured cells of humans and other species, a discovery that raises concerns about potential outbreaks in people. Researchers at The Ohio State University and Utrecht University in the Netherlands collaborated to better understand the new virus identified as porcine deltacoronavirus. Their study appears online in the journal PNAS. Scientists say the virus was first discovered in pigs in China in 2012. It was first detected in the United States in 201...
Conclusions This hospital outbreak demonstrated the difficulties in diagnosing pneumonia in patients with renal and cardiac failure, which leads to delayed suspicion of MERS-CoV and hence delay in applying the proper infection control procedures. In MERS-CoV endemic countries there is an urgent need for developing rapid point-of-care testing that would assist emergency department staff in triaging suspected cases of MERS-CoV to ensure timely isolation and management of their primary illness and prevent major MERS-CoV outbreaks.
The Middle East respiratory syndrome coronavirus (MERS-CoV) is a pathogen of zoonotic reservoir that has caused many outbreaks in healthcare settings, involving many healthcare workers (HCWs) (Alfaraj et al., 2018a; Memish and Al-Tawfiq, 2014). As of February 2018, a total of 2143 laboratory-confirmed cases of infection with MERS-CoV including 750 deaths had been reported globally from 27 countries, including 12 countries of the Middle East (Anon, 2018). Emergency departments have been highlighted as the initial site of the spread of this virus in most of the recent outbreaks (Ghazal et al., 2017; Assiri et al., 2013; Balkhy et al., 2016).
ConclusionPVP-I 7% gargle/mouthwash showed rapid bactericidal activity and virucidal efficacy in vitro at a concentration of 0.23% PVP-I and may provide a protective oropharyngeal hygiene measure for individuals at high risk of exposure to oral and respiratory pathogens.FundingMundipharma Research GmbH&Co. KG (MRG).
Disease news outbreak for MERS_CoV in Oman.
Conclusions It is necessary to examine the difficulties and demands of healthcare providers for establishing a safe healthcare system to respond effectively when national disasters occur. In addition, it is necessary to develop strategies to protect healthcare providers from severe physical and psychological stress.
CONCLUSION: As for MERS Co-V infections, underlying comorbidities impacted the clinical outcomes of OC43 infections. PMID: 29402475 [PubMed - as supplied by publisher]
Between 9 December 2017 and 17 January 2018, the National IHR Focal Point of The Kingdom of Saudi Arabia reported 20 additional cases of Middle East Respiratory Syndrome (MERS), including eight deaths. In addition, one death from a previously reported case was reported to WHO.