Ecology of Emerging Zoonotic Diseases

Centers for Disease Control and Prevention. 11/02/2017 This one-hour, four-minute webinar describes how human activities drive zoonotic disease emergence, including examples of human behaviors that promote increased contact with wildlife. It describes key elements of an ecological study of zoonotic diseases, lists effective interventions that reduce the risk of spillover of pathogens to humans from wildlife, explains how Nipah virus and Ebola emerged and why we continue to see outbreaks, and explains why wildlife surveillance is important for protecting human and livestock health. (Video or Multimedia)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Authors: Source Type: news

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[Malawi News Agency] Lilongwe -The Ministry of Health and Population has stressed the need for the country to stay prepared for Ebola disease even though there has been no single confirmed case registered in the country.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
koh Disease outbreaks caused by the ingestion of contaminated vegetables and fruits pose a significant problem to human health. The sources of contamination of these food products at the preharvest level of agricultural production, most importantly, agricultural soil and irrigation water, serve as potential reservoirs of some clinically significant foodborne pathogenic bacteria. These clinically important bacteria include: Klebsiella spp., Salmonella spp., Citrobacter spp., Shigella spp., Enterobacter spp., Listeria monocytogenes and pathogenic E. coli (and E. coli O157:H7) all of which have the potential to cause dise...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Review Source Type: research
[WHO] Abuja -In the short time it has existed, Nigeria's public health institute, the Nigeria Centre for Disease Control (NCDC), has reported, averted and controlled a myriad of disease outbreaks. A key factor in preventing either the occurrence or the spread of these outbreaks has been their early detection.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
This study presents the first evidence that the transcriptional regulator VjbR has important function in B. canis. In addition, according to its reduced virulence and the protective immunity it induces in mice, it can be a potential live attenuated vaccine against B. canis.
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Publication date: Available online 8 November 2019Source: Microbial PathogenesisAuthor(s): Maryam Dadar, Youcef Shahali, Yadolah FakhriAbstractBrucella spp. Is Gram-negative coccobacilli that may grow in different media and environmental conditions for extended periods of time. The survivals of these bacteria in the environment have an important impact on the epidemiology of brucellosis worldwide. The effect of climate on the incidence of certain zoonotic infectious diseases, (recently referred to as climate-sensitive zoonosis) is now well established. The aim of this study was to evaluate the relation between the incidenc...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
In this study, sixty significant differentially expressed genes were screened between susceptible and resistant sheep macrophages by transcriptome RNA-seq. Eight significantly enriched GO terms and six canonical pathways were involved by GO and KEGG enrichment analysis. Furthermore, the function of HMOX1, SLPI and SPP1 was verified by siRNA, which the knockdown of HMOX1 and SLPI increased remarkably the clearance of S. typhimurium, but SPP1 had little effect on the clearance of S. Typhimurium within sheep macrophages. Altogether, these results suggest that many genes of macrophages were reprogrammed via S. Typhimurium infe...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Vincent visits the Smithsonian Institution and speaks with Sabrina Sholts, Jon Epstein, and Ed Niles about the exhibit Outbreak: Epidemics in a Connected World. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&gt;&lt;/span&gt;&amp;lt;span […]
Source: virology blog - Category: Virology Authors: Tags: This Week in Virology ebola virus epidemic influenza virus MERS National Museum of Natural History Nipah virus One Health outbreak SARS smallpox virus Smithsonian spillover viral viruses zoonosis zoonotic Source Type: blogs
In this study, we evaluated the antiviral activity of the nucleoside analog 4′-azidocytidine (4′N3-C, R1479) and its 2′-monofluoro- and 2′-difluoro-modified analogs (2′F-4′N3-C and 2′diF-4′N3-C) against representative paramyxoviruses (Nipah virus, Hendra virus, measles virus, and human parainfluenza virus 3) and filoviruses (Ebola virus, Sudan virus, and Ravn virus). We observed enhanced antiviral activity against paramyxoviruses with both 2′diF-4′N3-C and 2′F-4′N3-C compared to R1479. On the other hand, while R1479 and 2′diF-4′N3-C inhibit...
Source: Antiviral Therapy - Category: Virology Source Type: research
In this study, we evaluated the antiviral activity of the nucleoside analog 4'-azidocytidine (4'N3-C, R1479) and its 2'-monofluoro- and 2'-difluoro-modified analogs (2'F-4'N3-C and 2'diF-4'N3-C) against representative paramyxoviruses (Nipah virus, Hendra virus, measles virus, and human parainfluenza virus 3) and filoviruses (Ebola virus, Sudan virus, and Ravn virus). We observed enhanced antiviral activity against paramyxoviruses with both 2'diF-4'N3-C and 2'F-4'N3-C compared to R1479. On the other hand, while R1479 and 2'diF-4'N3-C inhibited filoviruses similarly to paramyxoviruses, we observed 10-fold lower filovirus inh...
Source: Antiviral Research - Category: Virology Authors: Tags: Antiviral Res Source Type: research
by Raina K. Plowright, Alison J. Peel, Daniel G. Streicker, Amy T. Gilbert, Hamish McCallum, James Wood, Michelle L. Baker, Olivier Restif Progress in combatting zoonoses that emerge from wildlife is often constrained by limited knowledge of the biology of pathogens within reservoir hosts. We focus on the host–pathogen dynamics of four emerging viruses associated with bats: Hendra, Nipah, Ebola, and Marburg viruses. Spillover of ba t infections to humans and domestic animals often coincides with pulses of viral excretion within bat populations, but the mechanisms driving such pulses are unclear. Three hypotheses dom...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
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