Clinical outcomes of asleep vs awake deep brain stimulation for Parkinson disease

Conclusions: Asleep DBS for PD improved motor outcomes over 6 months on par with or better than awake DBS, was superior with regard to speech fluency and quality of life, and should be an option considered for all patients who are candidates for this treatment. Clinicaltrials.gov identifier: NCT01703598. Classification of evidence: This study provides Class III evidence that for patients with PD undergoing DBS, asleep intraoperative CT imaging–guided implantation is not significantly different from awake microelectrode recording–guided implantation in improving motor outcomes at 6 months.
Source: Neurology - Category: Neurology Authors: Tags: Parkinson's disease/Parkinsonism ARTICLE Source Type: research