Simple Skin Test May Help Identify Schizophrenia Simple Skin Test May Help Identify Schizophrenia

A niacin skin-flushing test may help identify patients with schizophrenia, new research shows.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Psychiatry News Source Type: news

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Authors: Desmettre T Abstract Nearly one-third of the planet's population is affected by T. gondii infection. In ophthalmology, toxoplasmosis is even considered to be the most common cause of posterior uveitis of infectious origin. Humans are only an intermediate host, and T. gondii needs to infect cats for its sexual reproduction. All the elements increasing the risk of predation by the definitive host are then favourable to the parasite. Numerous experimental animal model studies have shown that T. gondii infection is associated with predatory risk behaviours such as an attraction of infected mice ...
Source: Journal Francais d Ophtalmologie - Category: Opthalmology Tags: J Fr Ophtalmol Source Type: research
Purpose of review The most recent studies published or initiated in the last 18 months, investigating cannabidiol in the treatment of symptoms of schizophrenia and related conditions are summarized, including observed tolerability and reported side-effects. Recent findings Recent studies focused on patients with sub-acute psychotic syndromes of schizophrenia, clinical high-risk state for psychosis (CHR-P), or frequent cannabis users, as well as cognitive functioning in chronic schizophrenia. There is further, although not consistent evidence for cannabidiol-reducing positive symptoms, but not negative symptoms. Eviden...
Source: Current Opinion in Psychiatry - Category: Psychiatry Tags: SCHIZOPHRENIA AND RELATED DISORDERS: Edited by Lynn E. DeLisi and Iris E.C. Sommer Source Type: research
Purpose of review Clinical practice guidelines (CPGs) do not usually offer a sex-specific approach for the management of schizophrenia. With this narrative review, we aim to give an integrated and synthesized overview of the current state of knowledge regarding sex-specific aspects in schizophrenia and how this topic may be adapted in the development of CPGs. Recent findings Recent studies further suggest sex-specific differences in epidemiologic features, the course of illness, underlying pathomechanisms, response likelihood to antipsychotic medication and differences in tolerability. Beyond this, selective estrogen ...
Source: Current Opinion in Psychiatry - Category: Psychiatry Tags: SCHIZOPHRENIA AND RELATED DISORDERS: Edited by Lynn E. DeLisi and Iris E.C. Sommer Source Type: research
Purpose of review Recently, it has been questioned whether the re-emergence of psychotic symptoms following antipsychotic discontinuation or dose reduction is attributable to underlying psychotic vulnerability or to rebound effects of chronic use of antipsychotic medication. It was repeatedly shown that relapse rates are high after discontinuation of maintenance treatment. A potential contributing factor could be the increase in density of postsynaptic dopamine D2 receptors in the striatum and the higher affinity of D2 receptors for dopamine after chronic blockade. Recent findings To date, little clinical evidence is ...
Source: Current Opinion in Psychiatry - Category: Psychiatry Tags: SCHIZOPHRENIA AND RELATED DISORDERS: Edited by Lynn E. DeLisi and Iris E.C. Sommer Source Type: research
Purpose of review The association between hallucinations and sensory loss, especially vision- and hearing-impairment, has been firmly established over the past years. The deafferentation theory, a decrease of the threshold for activation in the brain and the consequential imbalance between excitatory and inhibitory brain networks, is hypothesized to underly this relationship. Here we review the studies investigating this theory with a focus on the most recent literature to better understand the contribution of sensory loss to hallucinations. Recent findings A large cross-sectional study has recently confirmed the rela...
Source: Current Opinion in Psychiatry - Category: Psychiatry Tags: SCHIZOPHRENIA AND RELATED DISORDERS: Edited by Lynn E. DeLisi and Iris E.C. Sommer Source Type: research
This article reviews current advances in evaluating the use of language as a diagnostic or prognostic tool in schizophrenia. Recent findings The development of computational linguistic tools to quantify language disturbances is rapidly gaining ground in the field of schizophrenia research. Current applications are the use of semantic space models and acoustic analyses focused on phonetic markers. These features are used in machine learning models to distinguish patients with schizophrenia from healthy controls or to predict conversion to psychosis in high-risk groups, reaching accuracy scores (generally ranging from 80 ...
Source: Current Opinion in Psychiatry - Category: Psychiatry Tags: SCHIZOPHRENIA AND RELATED DISORDERS: Edited by Lynn E. DeLisi and Iris E.C. Sommer Source Type: research
Purpose of review To summarize the current literature regarding comorbid schizophrenia and opioid use disorder (OUD). Recent findings Epidemiological evidence is unclear on whether patients with schizophrenia have a higher rate of OUD. Patients with OUD have been shown to have a higher risk of developing schizophrenia. However, it is clear that patients with both schizophrenia and OUD are less likely to receive standard of care including medication-assisted treatment (MAT) for opiate use disorder and have worse outcomes compared with patients with schizophrenia who do not abuse opioids. OUD significantly increases the...
Source: Current Opinion in Psychiatry - Category: Psychiatry Tags: SCHIZOPHRENIA AND RELATED DISORDERS: Edited by Lynn E. DeLisi and Iris E.C. Sommer Source Type: research
Purpose of review The gut microbiota has been speculated to underpin metabolic changes associated with chronic antipsychotic use. The change in the gut microbiota can also cause abnormal absorbtion from the gut into the blood stream (leaky gut syndrome) that can lead to inflammatory reactions, and thus, secondary damage to the brain and central nervous system. Our article aims to highlight relevant research on antipsychotic's effect on the microbiota and to point out future directions. Recent findings Antipsychtoic use can result in specific microbiota changes, and it is important to differentiate this from the innate...
Source: Current Opinion in Psychiatry - Category: Psychiatry Tags: SCHIZOPHRENIA AND RELATED DISORDERS: Edited by Lynn E. DeLisi and Iris E.C. Sommer Source Type: research
An unprecedented new study deepens the understanding of the genetic triggers that lead to conditions like autism spectrum disorder and schizophrenia.
Source: Yale Science and Health News - Category: Universities & Medical Training Source Type: news
Conditions:   Depression;   Catatonia;   Schizophrenia;   Schizoaffective Disorder;   Suicidal Intention;   Malignant Neuroleptic Intervention:   Sponsor:   Klinički Bolnički Centar Zagreb Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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