Synthesis, characterization and photophysical properties of a new Cu2+ selective phosphorescent sensor

Publication date: 15 December 2017 Source:Journal of Organometallic Chemistry, Volume 853 Author(s): Tianzhi Yu, Qianguang Yang, Zeyang Zhu, Yuling Zhao, Xiaoxiao Liu, Chengjin Wei, Hui Zhang A new Cu(II) selective phosphorescent sensor based on a cationic iridium(III) complex was synthesized and characterized. Compared with other commonly coexisting metal ions, the Ir(III) complex displayed significant phosphorescence quenching for detecting Cu2+ with a 1:1 stoichiometry in MeOH/H2O (1:1, v/v) solution. Upon addition of Cu2+, the rapid quenching of emission intensity provided a sensitive method for detection of Cu2+. The corresponding detection limit was determined to be 7.6 × 10−8 M and the association constant between the Ir(III) complex and Cu2+ was calculated to be 0.31 × 105 M−1. Luminescence imaging experiments demonstrated that this Ir(III) complex was cell permeable and suitable for monitoring intracellular Cu2+ in living Hela cells by confocal microscopy. Graphical abstract

Source: Journal of Organometallic Chemistry - November 6, 2017 Category: Chemistry Source Type: research