Mononuclear homoleptic organotin(IV) dithiocarbamates: Syntheses, structures and antimicrobial activities

Publication date: 15 December 2017 Source:Journal of Organometallic Chemistry, Volume 853 Author(s): Mamata Mahato, Shayantan Mukherji, Kristof Van Hecke, Klaus Harms, Abhrajyoti Ghosh, Hari Pada Nayek Six mononuclear organotin(IV) complexes of two dithiocarbamato ligands, [Ph3SnL1] (1), [Bu2Sn(L1)2] (2), [Ph2Sn(L1)Cl] (3), [Ph2Sn(L1)2] (4), [Ph2Sn(L2)2] (5) and [Ph3Sn(L2)] (6) where L 1  = thiomorpholine-4-carbodithiolate and L 2  = 2,6-dimethylmorpholine-4-carbodithiolate have been synthesized in good yields. Both ligands and complexes 1–6 were characterized by elemental analyses, FT-IR spectroscopy, UV-visible spectroscopy and 1H, 13C{1H} 119Sn{1H} NMR spectroscopy. In addition, the solid-state structures of the complexes were established through single-crystal X-ray diffraction analyses. The X-ray analyses reveal that the Sn(IV) center is five-coordinated in 1, 3 and 6. In complexes 2, 4 and 5, Sn(IV) is six-coordinated and occupies the center of a distorted octahedron. Moreover, an asymmetric coordination mode of the dithiocarbamato ligands was observed in all complexes. The optical properties and thermal stabilities of all complexes were investigated. All complexes were evaluated for their in vitro antimicrobial properties against E. coli. Complex 1 shows a maximal biological activity whereas the least activity is found for complex 6. Graphical abstract
Source: Journal of Organometallic Chemistry - Category: Chemistry Source Type: research

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