Next-Generation Sequencing Analysis and Algorithms for PDX and CDX Models

This study describes a sensitive method to identify contaminating host reads in xenograft and explant DNA- and RNA-Seq data and is applicable to other forms of deep sequencing. Mol Cancer Res; 15(8); 1012–6. ©2017 AACR.

http://mcr.aacrjournals.org/cgi/content/short/15/8/1012?rss=1

Source: Molecular Cancer Research - August 1, 2017 Category: Cancer & Oncology Authors: Khandelwal, G., Girotti, M. R., Smowton, C., Taylor, S., Wirth, C., Dynowski, M., Frese, K. K., Brady, G., Dive, C., Marais, R., Miller, C. Tags: Genomics Source Type: research