Cell-Free Circulating DNA Integrity Based on Peripheral Blood as a Biomarker for Diagnosis of Cancer: A Systematic Review

Conclusions: This review suggests that cfDI is controversial as a blood-based biomarker of cancers, although the sensitivity and AUC were relatively high.
Impact: cfDI shows heterogeneity between different studies; more perspective studies are needed to further assess its diagnostic performance, especially with other markers in combination. Cancer Epidemiol Biomarkers Prev; 26(11); 1595–602. ©2017 AACR.

Source: Cancer Epidemiology Biomarkers and Prevention - October 31, 2017 Category: Cancer & Oncology Authors: Cheng, J., Tang, Q., Cao, X., Burwinkel, B. Tags: Reviews Source Type: research