Towards an in-plane methodology to track breast lesions using mammograms and patient-specific finite-element simulations.

Towards an in-plane methodology to track breast lesions using mammograms and patient-specific finite-element simulations. Phys Med Biol. 2017 Nov 01;62(22):8720-8738 Authors: Lapuebla-Ferri A, Cegoñino-Banzo J, Jiménez-Mocholí AJ, Del Palomar AP Abstract In breast cancer screening or diagnosis, it is usual to combine different images in order to locate a lesion as accurately as possible. These images are generated using a single or several imaging techniques. As x-ray-based mammography is widely used, a breast lesion is located in the same plane of the image (mammogram), but tracking it across mammograms corresponding to different views is a challenging task for medical physicians. Accordingly, simulation tools and methodologies that use patient-specific numerical models can facilitate the task of fusing information from different images. Additionally, these tools need to be as straightforward as possible to facilitate their translation to the clinical area. This paper presents a patient-specific, finite-element-based and semi-automated simulation methodology to track breast lesions across mammograms. A realistic three-dimensional computer model of a patient's breast was generated from magnetic resonance imaging to simulate mammographic compressions in cranio-caudal (CC, head-to-toe) and medio-lateral oblique (MLO, shoulder-to-opposite hip) directions. For each compression being simulated, a virtual mammogram was obtained and posteri...
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research

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Abstract Breast cancer is a main cause of disease and death for women globally. Because of the limitations of traditional mammography and ultrasonography, magnetic resonance imaging (MRI) has gradually become an important radiological method for breast cancer assessment over the past decades. MRI is free of the problems related to radiation exposure and provides excellent image resolution and contrast. However, a disadvantage is the injection of contrast agent, which is toxic for some patients (such as patients with chronic renal disease or pregnant and lactating women). Recent findings of gadolinium deposits in t...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
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Source: Journal of General Internal Medicine - Category: Internal Medicine Source Type: research
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Source: radRounds - Category: Radiology Authors: Source Type: blogs
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Source: IRBM - Category: Biomedical Engineering Source Type: research
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