Aubergine and piRNAs promote germline stem cell self-renewal by repressing the proto-oncogene Cbl

This study reveals the role of piRNAs and PIWI proteins in controlling stem cell homeostasis via translational repression and highlights piRNAs as major post-transcriptional regulators in key developmental decisions.

Source: EMBO Journal - November 2, 2017 Category: Molecular Biology Authors: Rojas-Rios, P., Chartier, A., Pierson, S., Simonelig, M. Tags: Development & Differentiation, RNA Biology, Stem Cells Articles Source Type: research