Addiction, the opioid crisis, and family pain
In 2015, the opioid crisis was escalating to emergency-level proportions, claiming as many lives as car accidents. As the daughter of a longtime drug addict, the current burgeoning opioid epidemic managed to be both familiar and strange to me at the same time. My mother developed her addictions during the height of drug epidemics that occurred in New York City in the mid-1980s. The timeframe also marked the infancy of the AIDS crisis and the height of Reagan-era “Just Say No” programs. Back then, addiction was treated and viewed more as a crime than a disease, supposedly committed by scoundrels and misfits. The theory held that respectable people did not associate with addicts, much less share their homes and their blood with them. The intense societal shaming and criminalization of her addictions led to more resistance by my mother to seek the treatment she needed, until she eventually stopped trying to quit altogether. The stigmatization of her disease impacted me profoundly as a child — almost as much as the regular abuses I endured from her due to her addictive behavior. Whether it was being the regular target of smacking, lying, spitting, stealing, or vicious name-calling, it stung all the more because society made me feel complicit by relation. I had no healthy outlet to vent my escalating outrage at my own victimization, at an age when I was too young to properly process or even fully understand what was happening. I learned to stay silent, to repress...
This debate pack outlines progress so far in implementing the cancer strategy and provides statistics on survival rates and the NHS cancer workforce. It also collates commentary and analysis from official, parliamentary and third sector organisations.
ABSTRACT Deciphering the complex milieu that makes up the tumor microenvironment (TME) and the signaling engaged by TME cytokines continues to provide novel targets for therapeutic intervention. The IL‐6 family member Oncostatin M (OSM) has recently emerged as a potent driver of tumorigenesis, metastasis and therapy failure, molecular programs most frequently attributed to IL‐6 itself. In a recent issue of The Journal of Pathology, Kucia‐Tran et al. describe how elevated Oncostatin M receptor (OSMR) expression results in a feed‐forward loop involving the de novo production of both OSM and OSMR to facilitate aggress...
This NIHR Signal finds that for western high-income countries such as the UK, an estimated 15% to 16% of cancers could be avoided by preventing diabetes, obesity or excess weight. Although the links between high BMI, diabetes and cancer have been known for some time, this study presents the first calculations of attributable risk for 175 countries. This represents the proportion of cancers that could be prevented if the risk factors were eliminated.
According to this study: Current or recent users of hormonal contraceptives are at higher risk for breast cancer than women who have never used hormonal contraceptives.The risk increases with the duration of use.
According to this study: In patients with subacromial shoulder pain, arthroscopic decompression surgery and investigational arthroscopy were not found to be clinically beneficial compared with no treatment.
Oncology Nurses' Knowledge, Confidence, and Practice in Addressing Caregiver Strain and Burden . Oncol Nurs Forum. 2018 Mar 01;45(2):187-196 Authors: Irwin MM, Dudley W, Northouse L, Berry DL, Mallory GA Abstract OBJECTIVES: To describe nurses' practices, confidence, and knowledge of evidence-based interventions for cancer caregiver strain and burden and to identify factors that contribute to these aspects. . SAMPLE & SETTING: 2,055 Oncology Nursing Society members completed an emailed survey. . METHODS & VARIABLES: Pooled analysis of survey results. Variables included the bas...
Outbreaks across the continent infected 21,000 and killed at least 35 people. Now governments are moving to make vaccinations mandatory.
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RHEUMATOID arthritis can cause pain in joints in the body, most commonly in the knee, hip and hands. Other symptoms include swelling and stiffness, but there are also more uncommon signs that indicate the condition.