Promising Pneumonia Vaccine Under Development

Animal tests showed an immune response to 72 of the 90 - plus known strains of S. pneumoniae
Source: Pulmonary Medicine News - Doctors Lounge - Category: Respiratory Medicine Tags: Family Medicine, Infections, Internal Medicine, Emergency Medicine, Pediatrics, Pulmonology, Journal, Source Type: news

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Conclusion The results obtained from this research shows, in general, the fragility in the social and political infrastructure necessary to improve the living conditions of populations, particularly those that depend on family agriculture in drought prone areas. The conditions of social, economic and environmental vulnerabilities presented in the region can be amplified by the drought process, and can aggravate the impacts resulting drought events, thus disadvantaging the population of this region, as shown in the Fig. 1. The general perception of the interviewees of the health sector shows an agreement with what is found...
Source: PLOS Currents Disasters - Category: International Medicine & Public Health Authors: Source Type: research
BOSTON (CBS) – Dog owners are being urged to vaccinate their pets as the first case of canine flu this year has been confirmed in Massachusetts. A six-month-old poodle was treated and released on Aug. 14 after a two-day stay at the MSPCA’s Angell Animal Medical Center. The MSPCA is urging owners of at-risk dogs to consider vaccinating their pets against the highly contagious virus for added protection. Veterinarians estimate that the the vaccine is about 60 percent effective. Dr. Virginia Sinnott of Angell’s Emergency &Critical Care Unit examines a dog after Massachusetts saw its first confirmed case ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Syndicated Local Angell Animal Medical Center dog flu MSPCA Source Type: news
Authors: Chen S, Tian X Abstract Human mastadenovirus (HAdVs) can cause a broad spectrum of diseases in both children and adults, including acute respiratory infection, gastroenteritis, epidemic keratoconjunctivitis. Populations susceptible to adenovirus infection include children, immunocompromised patients and military recruits. To date, seven species (A-G) including more than 79 genotypes have been characterized, of which HAdV-B3, B4, B7 and the recently reemerged types 14 and 55 often lead to severe pneumonia. The live oral enteric-coated adenovirus type 4 and 7 vaccine, which was approved for use in US militar...
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
AbstractPneumonic pasteurellosis is an economically important infectious disease in the small ruminant industry which causes sudden death and loss for farmers. Nonetheless, this disease is still a common sight in sheep and goats in Malaysia, probably due to the unpopular usage of pasteurellosis vaccine or inappropriate vaccination practices. The aim of this study was designed to classify the severity of pneumonia via the establishment of auscultation scoring method and to quantify the acute phase proteins and heat shock proteins responses from vaccinated and non-vaccinated goats. Goat farms, consist of vaccinated and non-v...
Source: Tropical Animal Health and Production - Category: Veterinary Research Source Type: research
Publication date: Available online 26 July 2018Source: Veterinary MicrobiologyAuthor(s): Yun Bai, Yuan Gan, Li-Zhong Hua, Heiko Nathues, Hao Yang, Yan-Na Wei, Meng Wu, Guo-Qing Shao, Zhi-Xin FengAbstractIn order to evaluate the sIgA-ELISA method reported previously for differentiating Mycoplasma hyopneumoniae (M. hyopneumoniae) infected from vaccinated pigs, dynamics of anti-M. hyopneumoniae secretory IgA (sIgA) antibody secretion in nasal mucus and IgG antibodies in serum from 10 pigs experimentally infected with M. hyopneumoniae or vaccinated with an inactivated vaccine were examined using sIgA-ELISA and a commercial M. ...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
CONCLUSION: These studies indicate that bDNA is effective as an immune adjuvant, and along with stimulatory bDNA represent promising new humoral and cellular immune enhancers for vaccination applications. In addition, this vaccine is able to provide long-term protection against infection. PMID: 30016232 [PubMed - as supplied by publisher]
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Tags: J Med Microbiol Source Type: research
Publication date: 1 September 2018Source: Preventive Veterinary Medicine, Volume 157Author(s): Louis Lignereux, Anne-Lise Chaber, Claude Saegerman, Lucía Manso-Silván, Armelle Peyraud, Andrea Apolloni, François ThiaucourtAbstractContagious caprine pleuropneumonia (CCPP), caused by Mycoplasma capricolum subsp.capripneumoniae, has long been considered a goat-specific disease. Since 2007 there has been growing evidence that this disease can affect wild ungulates either kept in captivity or in the wild. In 2013, a large collection of sand gazelles (Gazella marica) held in the United Arab Emirates suffered ...
Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
Publication date: June 2018Source: Research in Veterinary Science, Volume 118Author(s): Bernadette Earley, Katie Tiernan, Catherine Duffy, Amanda Dunn, Sinead Waters, Steven Morrison, Mark McGeeAbstractThe study objectives were: 1) to characterise the development of immunocompetence in beef suckler calves from birth to three months of age, and 2) to trace glycoprotein E (gE)-negative bovine herpesvirus type 1 (BoHV-1) antibodies from dam to calf and subsequent vaccination against pneumonia. Thirty multiparous beef suckler, spring-calving cows, consisting of two genotypes were involved; Limousin × Friesian (...
Source: Research in Veterinary Science - Category: Veterinary Research Source Type: research
Publication date: 1 September 2018Source: Preventive Veterinary Medicine, Volume 157Author(s): Louis Lignereux, Anne-Lise Chaber, Claude Saegerman, Lucía Manso-Silván, Armelle Peyraud, Andrea Apolloni, François ThiaucourtAbstractContagious caprine pleuropneumonia (CCPP), caused by Mycoplasma capricolum subsp.capripneumoniae, has long been considered a goat-specific disease. Since 2007 there has been growing evidence that this disease can affect wild ungulates either kept in captivity or in the wild. In 2013, a large collection of sand gazelles (Gazella marica) held in the United Arab Emirates suffered ...
Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
Streptococcus pneumoniae (S. pneumonia), bacteria commonly referred to as pneumococcus, are a significant cause of disease resulting in 1.5 million deaths every year worldwide according to the World Health Organization. The major types of pneumococcal disease are pneumonia (lung infection), bacteremia (bloodstream infection), and meningitis (infection of the tissue covering of the brain and spinal cord). Less severe pneumococcal illnesses include ear and sinus infections.CDC scientists have developed a specific amino acid sequence, the P4 peptide, of the Pneumococcal surface adhesin A (PsaA) protein which is an immunogenic...
Source: NIH OTT Licensing Opportunities - Category: Research Authors: Source Type: research
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