Dupilumab Breathes Optimism Into Biologics for Asthma Dupilumab Breathes Optimism Into Biologics for Asthma
Patients with severely uncontrolled asthma derive the most benefit from dupilumab, a new study shows, building enthusiasm for phase 3 results.Medscape Medical News
Conditions: Acute Asthma; Acute Wheezy Bronchitis Interventions: Drug: Montelukast 4 Mg Oral Granule; Drug: Placebos Sponsor: Kecioren Education and Training Hospital Completed
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A look at how to make yourself sneeze. Included is detail on the causes of a sneeze and the best ways to trigger a sneeze to relieve congestion.
CONCLUSION: There was no evidence of an association between BMI and frequency of ED visits and hospitalization for asthma exacerbation among children. LIMITATIONS: This study included patients as young as 2 years, while asthma is only well-defined in children>5 years. Asthma triggers that can cause exacerbation despite body weight were not included. We included only frequency of ED visits and hospitalization, which may be inadequate to measure asthma severity.
This study investigates the prevalence and types of effects of fragranced products on asthmatics in the American population. Using a nationally representative sample (n = 1137), data were collected with an on-line survey of adults in the USA, of which 26.8% responded as being medically diagnosed with asthma or an asthma-like condition. Results indicate that 64.3% of asthmatics report one or more types of adverse health effects from fragranced products, includi ng respiratory problems (43.3%), migraine headaches (28.2%), and asthma attacks (27.9%). Overall, asthmatics were more likely to experience adverse hea...
Abstract BackgroundPrevious studies examining high‐frequency emergency department (ED) utilization have primarily used single‐center data, potentially leading to ascertainment bias if patients visit multiple centers. The goals of this study were 1) to create a predictive model to prospectively identify patients at risk of high‐frequency ED utilization for asthma and 2) to examine how that model differed using statewide versus single‐center data. MethodsTo track ED visits within a state, we analyzed 2011 to 2013 data from the New York State Healthcare Cost and Utilization Project State Emergency Department Databases...
Asthma is the most prevalent chronic disease of childhood. Recently, we identified a critical window early in the life of both mice and Canadian infants during which gut microbial changes (dysbiosis) affect asthma development. Given geographic differences in human gut microbiota worldwide, we studied the effects of gut microbial dysbiosis on atopic wheeze in a population living in a distinct developing world environment.
Abstract Background: The worldwide increase in the prevalence of asthma has made it a major public‐health concern. We aimed to identify the prevalence of asthma and asthma symptoms in adults living in urban and rural areas of Iran as a populated country with about 80 millions of residents. Methods: This cross‐sectional study was conducted to estimate the prevalence of asthma in adults between 20 to 44 years old in all provinces of Iran. Data were collected by personal interview via a standardized questionnaire (European Community Respiratory Health Survey (ECRHS)) between November 2015 and February 2016. Results: A tot...
ABSTRACT Background: Blood biomarkers are easily accessible and might reflect chronic obstructive pulmonary disease (COPD) activity. Aim: To determine whether a panel of blood biomarkers (C‐reactive protein [CRP], neutrophils, eosinophils, albumin and vitamin D) could predict mortality in COPD. Methods: we analyzed data from 431 COPD participants to the 2007‐2010 National Health and Nutrition Examination Surveys who were followed for a median time of 36 months. COPD was defined as post‐bronchodilator forced expiratory volume in 1 second (FEV1) and forced vital capacity ratio
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