The effect of adjuvant chemotherapy on survival and recurrence after curative rectal cancer surgery in patients who are histologically node negative after neoadjuvant chemoradiotherapy
ConclusionThis study found no significant difference in survival or disease recurrence between patients who received adjuvant chemotherapy and patients who did not. There is no clear evidence to support or dismiss the use of adjuvant chemotherapy for patients who were node positive on preoperative MRI and node negative on histopathological staging. Further multicentre prospective randomized trials are needed to identify the appropriate treatment regime for this group of patients.
Source: Colorectal Disease - Category: Gastroenterology Authors: D. L. H. Baird, Q. Denost, C. Simillis, G. Pellino, S. Rasheed, C. Kontovounisios, P. P. Tekkis, E. Rullier Tags: Original Article Source Type: research
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