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Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news

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CONCLUSION: The C. cyminum L. and C. sativum L EOs could be good alternative to protect foods. PMID: 30221882 [PubMed - in process]
Source: Pakistan Journal of Biological Sciences: PJBS - Category: Biomedical Science Authors: Tags: Pak J Biol Sci Source Type: research
Christine Schoeler Jepsen, Lalit Kumar Dubey, Kimmie B. Colmorten, Jesper B. Moeller, Mark A. Hammond, Ole Nielsen, Anders Schlosser, Steven P. Templeton, Grith L. Sorensen, Uffe Holmskov
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Yonghong Liu Two new alkaloids, fumigatosides E (1) and F (2), and a new natural product, 3, 7-diketo-cephalosporin P1 (6) along with five known compounds (3–5, 7, 8) were isolated from deep-sea derived fungal Aspergillus fumigatus SCSIO 41012. Their structures were determined by extensive spectroscopic data analysis, including 1D, 2D nuclear magnetic resonance (NMR) and mass spectrometry (MS), and comparison between the calculated and experimental electronic circular dichroism (ECD) spectra. In addition, all compounds were tested for antibacterial and antifungal inhibitory activities. Compound 1 showed si...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Glucocorticoids are the most widely used agents in the treatment of allergic bronchopulmonary aspergillosis (ABPA), a disorder characterised by immunologic reactions mounted against Aspergillus fumigatus colonising the airways of patients with asthma and cystic fibrosis [1, 2]. Unfortunately, the use of glucocorticoids is associated with several adverse reactions [3]. A novel treatment strategy in ABPA would be the use of antifungal triazoles as monotherapy. Recently, we have shown that itraconazole was effective as monotherapy in acute-stage ABPA [4]. Whether voriconazole monotherapy is also efficacious in acute-stage ABPA remains unknown.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Articles: Research letters Source Type: research
Publication date: Available online 16 September 2018Source: Biochemical Engineering JournalAuthor(s): Hisanori Iwasa, Kazumichi Ozawa, Noriko Sasaki, Nao Kinoshita, Kenji Yokoyama, Atsunori HiratsukaAbstractSix FAD-dependent glucose dehydrogenase (FAD-GDH) genes, for blood glucose sensors, from the genomic DNAs of Aspergillus species were identified by degenerated PCR screening. The enzymatic properties of the gene products expressed by Pichia pastoris were characterized. Investigation of substrate selectivity to fourteen saccharides revealed that these enzymes were maltose-insensitive FAD-GDHs. A.bisporus, A.terreus var. ...
Source: Biochemical Engineering Journal - Category: Biochemistry Source Type: research
AbstractAirborne fungal spores are well documented to trigger respiratory allergy. The present study provides baseline information on the quantitative and qualitative aspects of aerospores for the first time in a typical urban area of Kolkata metropolis, India. An aeromonitoring was performed by Burkard volumetric 7-day sampler for two consecutive years (August 2012 –July 2014). Total concentration, seasonal variations and intradiurnal periodicities of fungal spores were estimated. Spearman’s rank correlation analysis was performed using various weather parameters. The prevalence of fungal spore allergy was inv...
Source: Aerobiologia - Category: Environmental Health Source Type: research
Aspergillus fumigatus is a ubiquitous saprotrophic fungus and an opportunistic pathogen of humans and animals. Humans and animals can inhale hundreds of A. fumigatus spores daily. Normally this is harmless for hu...
Source: BMC Microbiology - Category: Microbiology Authors: Tags: Research article Source Type: research
In this study, two new compounds with a prenylated diphenyl ether structure—diorcinol L (1) and (R)-diorcinol B (2)—were isolated from the marine algal-derived endophytic fungus Aspergillus tennesseensis, along with seven known compounds: (S)-diorcinol B (3), 9-acetyldiorcinol B (4), diorcinol C (5), diorcinol D (6), diorcinol E (7), diorcinol J (8), and a dihydrobenzofuran derivative 9. Their structures were elucidated by extensive NMR spectroscopy studies. Compound 2 represents the first example of an R-configuration in the prenylated moiety. All these isolated compounds were examined for antimicrobia...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Conclusions: β-glucan can be used to establish the diagnosis of chronic fungal rhinosinusitis. However, differential diagnosis of allergy or infection cannot be excluded by examination of blood NER. Still, it is hoped that the process of diagnosis can be obtained quickly and precisely without the need for invasive procedure although it requires more research, especially related to the diagnostic test. PMID: 30210718 [PubMed]
Source: Oman Medical Journal - Category: Middle East Health Tags: Oman Med J Source Type: research
Authors: Sehgal IS, Dhooria S, Behera D, Agarwal R Abstract Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder that results from immune responses mounted against antigens of Aspergillus fumigatus, resulting in non-specific respiratory symptoms and structural lung damage. Classically defined in individuals suffering from bronchial asthma and cystic fibrosis, ABPA has recently been described in other lung diseases including COPD, pulmonary tuberculosis, idiopathic bronchiectasis and others. Herein, we report the first case of ABPA complicating Swyer-James-Macleod's syndrome that was successfully t...
Source: European Annals of Allergy and Clinical Immunology - Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
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