Mefloquine for preventing malaria during travel to endemic areas.

CONCLUSIONS: The absolute risk of malaria during short-term travel appears low with all three established antimalarial agents (mefloquine, doxycycline, and atovaquone-proguanil).The choice of antimalarial agent depends on how individual travellers assess the importance of specific adverse effects, pill burden, and cost. Some travellers will prefer mefloquine for its once-weekly regimen, but this should be balanced against the increased frequency of abnormal dreams, anxiety, insomnia, and depressed mood.
PMID: 29083100 [PubMed - as supplied by publisher]

Source: Cochrane Database of Systematic Reviews - October 30, 2017 Category: General Medicine Authors: Tickell-Painter M, Maayan N, Saunders R, Pace C, Sinclair D Tags: Cochrane Database Syst Rev Source Type: research