An alternative approach identified optimal risk thresholds for treatment indication: an illustration in coronary heart disease

Treatment thresholds based on risk predictions can be optimized by considering various health (economic) outcomes and performing marginal analyses, but this is rarely performed. We demonstrate a general approach to identify treatment thresholds optimizing individual health (economic) outcomes, illustrated for statin treatment based on 10-year coronary heart disease (CHD) risk predicted by the Framingham risk score.
Source: Journal of Clinical Epidemiology - Category: Epidemiology Authors: Tags: Original Article Source Type: research