An alternative approach identified optimal risk thresholds for treatment indication: an illustration in coronary heart disease
Treatment thresholds based on risk predictions can be optimized by considering various health (economic) outcomes and performing marginal analyses, but this is rarely performed. We demonstrate a general approach to identify treatment thresholds optimizing individual health (economic) outcomes, illustrated for statin treatment based on 10-year coronary heart disease (CHD) risk predicted by the Framingham risk score.
Source: Journal of Clinical Epidemiology - Category: Epidemiology Authors: Anoukh van Giessen, G. Ardine de Wit, Karel G.M. Moons, Jannick A.N. Dorresteijn, Hendrik Koffijberg Tags: Original Article Source Type: research
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