Stem cells conduct cartilage regeneration but are not directly involved
(University of Veterinary Medicine -- Vienna) For stem cell therapy it has remained unclear whether stem cells are responsible for regeneration of cartilage damage or whether they trigger the curing. Researchers at Vetmeduni Vienna have now been able to resolve this. After injection, stem cells orchestrate the healing effect of endogenous cells but are not responsible for cartilage regeneration. The breakthrough published in JCI-Insight was enabled by preventing the normal immune response to the molecule required to trace the injected cells.
Source: EurekAlert! - Biology - Category: Biology Source Type: news