Pioglitazone stabilizes atherosclerotic plaque by regulating the Th17/Treg balance in AMPK-dependent mechanisms

Pioglitazone (PIO), a thiazolidinediones drug, is a well-known anti-diabetic medicine, but its anti-atherosclerotic effects remain controversial. Thus it is important to investigate the effects of PIO on ather...
Source: Cardiovascular Diabetology - Category: Cardiology Authors: Tags: Original investigation Source Type: research

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CONCLUSION: When comparing the basic and extended foot care education means scores, participants had less extended foot care knowledge than basic foot care knowledge. This study also showed that insurance status had considerable influence on extended foot care knowledge. In an African American population with T2DM, regardless of education and gender, there are considerable differences between how foot care knowledge is translated into actual foot self-care behaviors. PMID: 30455120 [PubMed - as supplied by publisher]
Source: Journal of the National Medical Association - Category: General Medicine Tags: J Natl Med Assoc Source Type: research
Researchers have developed a tool that diagnoses high blood sugar levels simply by analysing the pattern of fluorescent light reflected off the skin
Source: New Scientist - Health - Category: Consumer Health News Source Type: research
Publication date: January–February 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &Reviews, Volume 13, Issue 1Author(s): Salwa Seddik Hosny, Merhan Samy Nasr, Rana Hashem Ibrahim, Zainb YousryHelalAbstractBackgroundPeripheral neuropathy is one of the most common complications of both type 1 and type 2 diabetes, Long standing peripheral neuropathic pain associated with peripheral neuropathy occurs in one of six diabetic subjects, Apelin is a peptide secreted from adipocytes that seems to be beneficial in early detection of diabetic neuropathy, Itisnotedthatitincreasesindiabeticpatients and more in...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
ConclusionsWe concluded that diabetes mellitus causes a significant impairment in pulmonary function test. This impairment is significantly related with proteinuria.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
ConclusionIn conclusion, markers of oxidative stress and inflammation should be taken into consideration while evaluating the risk for CVD in prediabetes since these markers were well correlated with glucose intolerance in prediabetic subjects.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
CONCLUSION: Epistaxis may be seen as a general marker of poor health and a poor prognostic sign. PMID: 30457066 [PubMed - as supplied by publisher]
Source: Journal of Laryngology and Otology - Category: ENT & OMF Tags: J Laryngol Otol Source Type: research
By 2030, about half of the 79 million adults around the globe predicted to have type 2 diabetes won't have access to insulin, a study said.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
ConclusionsComprehensive evaluation of real-world data suggests an average DEXi duration close to five months, following a PRN treatment strategy, including about 1/3 of patients. Repeated DEXi administration revealed an acceptable long-term efficacy/safety ratio.
Source: Journal of Pharmacological Sciences - Category: Drugs & Pharmacology Source Type: research
Conclusion: This study suggests the potential effect of BCP in treating HFFD-induced metabolic and neurobehavioral alterations. BCP seems to activate PPAR-γ in a ligand-independent manner, via upregulation and activation of PGC-1α. The BCP activation of PPAR--γ seems to be CB2R-dependent.Graphical abstract
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Medtronic (NYSE:MDT) said today that it inked a deal to acquire nutrition tech company Nutrino Health for an undisclosed amount, with plans on integrating it into the company’s diabetes division. Nutrino Health provides nutrition-related data services, analytics and technologies, Fridley, Minn.-based Medtronic said. The company said it plans to integrate Nutrino’s food analysis infrastructure, nutrition science expertise and artificial intelligence-driven personalized insights into its diabetes platform. Read the whole story on our sister site, Drug Delivery Business News The post Medtronic inks deal to ac...
Source: Mass Device - Category: Medical Devices Authors: Tags: Business/Financial News Diabetes Featured Mergers & Acquisitions Medtronic nutrinohealth Source Type: news
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