Mitochondrial targeted curcumin exhibits anticancer effects through disruption of mitochondrial redox and modulation of TrxR2 activity.

This study also demonstrates the role of TrxR2 and mitochondrial DNA damage in mitocurcumin mediated killing of cancer cells.
PMID: 29080841 [PubMed - as supplied by publisher]

Source: Free Radical Biology and Medicine - October 25, 2017 Category: Biology Authors: Jayakumar S, Patwardhan RS, Pal D, Singh B, Sharma D, Kutala VK, Kumar Sandur S Tags: Free Radic Biol Med Source Type: research