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Dementia diet: Drink costing less than £4 has been shown to delay onset of Alzheimer's

DEMENTIA risk is known to be reduced by omega-3. Now researchers have created a drink containing fatty acids, vitamins and other nutrients that they say slows onset of Alzheimer ’s disease.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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The Lancet Commission (Dec 16, 2017, p 2673)1 on prevention and management of dementia reviews the mounting evidence that hearing loss is a major risk factor for cognitive decline. Crucial information is still absent about the nature of this linkage and what factors might modify the cognitive effect of peripheral hearing loss. Particularly, the potential relevance of central hearing impairment should not be underestimated. As Gill Livingston and colleagues1 acknowledge, on pathophysiological and neuroanatomical grounds, central auditory processing is likely to be susceptible early in the course of Alzheimer's disease and other dementias.
Source: LANCET - Category: General Medicine Authors: Tags: Correspondence Source Type: research
After heart disease and cancer, Alzheimer ’s disease and dementia are the leading cause of death for seniors, responsible for one out of every three deaths. Today, the disease devastates the minds of people of all ages and creates substantial burdens for families and caregivers. By 2060, the number of patients affected is expected to doub le from 5 million to 10 million.
Source: The Catalyst - Category: Pharmaceuticals Tags: Medicines in Development Research and Development Alzheimer's Source Type: news
The open access paper noted here reports on the use of a genetic analysis to shed further light on the relative importance of shared mechanisms across a range of neurodegenerative conditions in which tau aggregation is thought to be important. The researchers find associations in gene expression between these conditions that suggesting microglial dysfunction is an important common determinant of disease progression. If one looks over all of the most common neurodegenerative diseases, patients exhibit a number of overlapping mechanisms that appear plausible as proximate causes of brain cell dysfunction and death. Som...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
AbstractThe focus of modern biomedical research concentrates on molecular level regulatory mechanisms and how the normal and abnormal phenotypes of tissue functional are affected by regulatory mechanisms. Most of the research on regulatory mechanism starts from the reconstruction of gene regulation network. At present, a large number of reconstruction methods construct the network using a single data set. These methods of inferring and predicting the relationship between the target gene and the transcription factor (TF) can be used to identify individual interactions between genes, while there is not much research on the i...
Source: Interdisciplinary Sciences, Computational Life Sciences - Category: Bioinformatics Source Type: research
Szilvássy Z, Juhász B Abstract Alzheimer's disease (AD) is a neurodegenerative disorder with cognitive impairment. Physical exercise has long been proven to be beneficial in the disorder. The present study was designed to examine the effect of voluntary exercise on spatial memory, imaging, and pathological abnormalities. Particular focus has been given to the role of heme oxygenase-1 (HO-1)-an important cellular cytoprotectant in preserving mental acuity-using an aging rat model of dementia. Male and female Wistar rats were segregated into six groups-namely, (i) aged sedentary (control) females (ASF,...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Abstract In elderly population, Alzheimer's disease is a common neurodegenerative disorder and accounts for about 70% of all cases of dementia. The neurodegenerative processes of this disease start presumably 20 years ahead of the clinical beginning of the disorder. The postmortem histopathological examination, brains from Alzheimer's disease patients with characteristic features like amyloid plaques and neurofibrillary tangles, neuronal and synaptic disintegration confirm the final diagnosis of Alzheimer's disease. Senile plaques are composed of -amyloid peptide, deriving from the amyloid protein precursor, wh...
Source: Folia Neuropathologica - Category: Pathology Authors: Tags: Folia Neuropathol Source Type: research
From our reader Judith:How do you get a urine sample from someone who doesn't understand what you're trying to do or resists the invasion of privacy?This is an excellent question and I have not written about this in some time. So here we go.Yes, getting a urine sample from a person living with dementia or an elderly person can be quite a task - sometimes near impossible.Well, I have a solution to this problem thatworks 100% of the time if the person can take a pee on a toilet.Did you know? An Undetected Urinary Tract Infection Can Kill an Alzheimer's Patientby Bob DeMarcoAlzheimer's Reading RoomSubscribe to the Alzheimer's...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: collecting a urine sample from a dementia patient how to get a urine sample from an elderly person urinary tract infection urine collection urine sample alzheimer urine sample dementia Source Type: blogs
Funding Opportunity PAR-18-760 from the NIH Guide for Grants and Contracts. To study in vivo synaptic structure and function in Alzheimer's and related dementia; and to advance development of methods to study synapses in animal models and humans.
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
Authors: Nielsen RE, Valentin JB, Lolk A, Andersen K Abstract OBJECTIVE: To investigate secular changes in mortality rates between patients with Alzheimer's disease (AD) and the general population as well as changes in antipsychotic drug treatment and the association between drug treatment and mortality in patients with AD in Denmark during a 12-year study period. METHODS: This nationwide, retrospective cohort study identified all-cause mortality in all Danish patients with incident ICD-10-defined AD from 2000 through 2011. The cumulative antipsychotic dosages from dementia diagnosis until end of study for each...
Source: Journal of Clinical Psychiatry - Category: Psychiatry Tags: J Clin Psychiatry Source Type: research
Publication date: Available online 17 April 2018 Source:Journal of Chemical Neuroanatomy Author(s): Jit Poddar, Munmun Pradhan, Gargi Ganguly, Sasanka Chakrabarti The aging of brain in the absence of neurodegenerative diseases, usually called non-pathological brain aging or normal cognitive aging, is characterized by an impairment of memory and cognitive functions. The underlying cellular and molecular changes in the aging brain that include oxidative damage, mitochondrial impairment, changes in glucose-energy metabolism and neuroinflammation have been reported widely from animal experiments and human studies. The cogniti...
Source: Journal of Chemical Neuroanatomy - Category: Neuroscience Source Type: research
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