Driving drug resistance out of fungi

(Wyss Institute for Biologically Inspired Engineering at Harvard) A collaborative team at Harvard's Wyss Institute for Biologically Inspired Engineering, has developed a CRISPR-Cas9-based 'gene drive' platform to create diploid strains of the pathogen in which both gene copies could be efficiently deleted. The technique may lead the way toward a better understanding of drug resistance and biofilm-forming mechanisms, and through future research, it could help pinpoint new drug targets and combination therapies. The study is published in Nature Microbiology.
Source: EurekAlert! - Biology - Category: Biology Source Type: news