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Trauma and amyotrophic lateral sclerosis: a European population-based case-control study from the EURALS consortium - Pupillo E, Poloni M, Bianchi E, Giussani G, Logroscino G, Zoccolella S, Chio A, Calvo A, Corbo M, Lunetta C, Marin B, Mitchell D, Hardiman O, Rooney J, Stevic Z, Bandettini di Poggio M, Filosto M, Cotelli MS, Perini M, Riva N, Tremolizzo L, Vitelli E, Damiani D, Beghi E.

OBJECTIVES: To assess the association between amyotrophic lateral sclerosis (ALS) and previous traumatic events, age of trauma, and site of injury. METHODS: A population-based case-control study was performed in five European countries (Italy, Irel...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

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Chronic traumatic encephalopathy (CTE) is the neurodegenerative disease of the moment, made famous by the violent and untimely deaths of many retired professional athletes. Repeated blows to the head sustained in contact sports such asboxing and American football can result in abnormal accumulations oftau protein (usually many years later). The autopsied brains from two of these individuals are shown below.Left: courtesy of Dr. Ann McKee inNYT. Right: courtesy of Dr. Bennett Omalu inCNN. These are coronal sections1 from the autopsied brains of: (L) Aaron Hernandez, aged 27; and(R) Fred McNeill, aged 63.Part 1 of this ...
Source: The Neurocritic - Category: Neuroscience Authors: Source Type: blogs
Head injury is considered as a potential risk factor for amyotrophic lateral sclerosis (ALS). However, several recent studies have suggested that head injury is not a cause, but a consequence of latent ALS. We aimed to evaluate such a possibility of revers...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
The question is not whether disruptive technologies will transform the healthcare job market, but rather how and when will it happen. Healthcare navigators, augmented/virtual reality operation planners and nanomedicine engineers in the second part of my article series about future jobs in healthcare. As I am certain that the huge waves of technological change transform the medical professional palette; based on the current and prospective trends in digital health technologies I envisioned what potential new professions could appear in our lives. Don’t miss the first part of the list! If you have an idea about another...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine artificial intelligence augmented reality brain-computer interface cyborg gamification gc4 Health Innovation nanotechnology Personalized medicine psychology robotics virtual reality Source Type: blogs
Editor's Note: This is the first of five articles this week by the labor and employment team at the law firm of Wright Lindsey Jennings of Little Rock examining key trends for employers and the workplace in 2017. Here's a quick look at important employment issues that could arise next year. Now that Arkansas is the latest state to have a medical marijuana law on the books, Arkansas employers must be prepared to address this issue. Although the amendment to the Arkansas Constitution is effective immediately, it should take some time for most Arkansas residents to take advantage of the approved use of medical ...
Source: Arkansas Business - Health Care - Category: American Health Source Type: news
Although more than $500 million in federally funded research on Persian Gulf War veterans has produced many findings, there has been little substantial progress in the overall understanding of health effects, particularly Gulf War illness, resulting from military service in the war, says a new Academies report. Aligning with conclusions in a 2010 report, the committee that carried out the latest study said veterans who were deployed to the Gulf War appear to have an increased risk for Gulf War illness, chronic fatigue syndrome, functional gastrointestinal conditions, and mental health disorders such as post-traumatic stres...
Source: News from the National Academies - Category: Science Source Type: news
Abstract As a low-affinity neurotrophins receptor, p75 neurotrophin receptor (p75NTR) is a transmembrane receptor involved in a diverse array of cellular responses, including apoptosis, survival, neurite outgrowth, migration, and cell cycle arrest, which may be related to some neurological disorders, such as Alzheimer's disease (AD), schizophrenia, major depressive disorder (MDD), posttraumatic stress disorder (PTSD), amyotrophic lateral sclerosis (ALS), and Parkinson's disease (PD). Indeed, a series of studies during the last decade has demonstrated that the p75NTR signaling plays key roles in most aspects of the...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - Category: Drugs & Pharmacology Authors: Tags: Biomed Pharmacother Source Type: research
Publication date: December 2015 Source:Biomedicine & Pharmacotherapy, Volume 76 Author(s): Ya-Hai Shu, Xiu-Min Lu, Jing-Xiang Wei, Lan Xiao, Yong-Tang Wang As a low-affinity neurotrophins receptor, p75 neurotrophin receptor (p75NTR) is a transmembrane receptor involved in a diverse array of cellular responses, including apoptosis, survival, neurite outgrowth, migration, and cell cycle arrest, which may be related to some neurological disorders, such as Alzheimer’s disease (AD), schizophrenia, major depressive disorder (MDD), posttraumatic stress disorder (PTSD), amyotrophic lateral sclerosis (ALS), and Par...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
This report demonstrates that hADSCs promote neuronal survival in the spinal ganglion, fuel axonal repair and stimulate the regeneration of peripheral nerves.
Source: Clinical and Experimental Medicine - Category: Research Source Type: research
Funding Opportunity Number: W81XWH-15-GWIRP-CTA Opportunity Category: DiscretionaryFunding Instrument Type: Cooperative AgreementGrantCategory of Funding Activity: Science and Technology and other Research and DevelopmentCFDA Number: 12.420Eligible Applicants Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"Agency Name: DOD-AMRAAClosing Date: Oct 29, 2015Award Ceiling: $0Expected Number of Awards: 1Creation Date: May 14, 2015Funding Opportunity Description: The FY15 GWIRP is offering two award mechani...
Source: Grants.gov - Category: Research Tags: Science and Technology and other Research and Development Source Type: funding
Abstract The present investigation aimed to provide an objective narrative review of the existing literature pertaining to the benefits and harms of marijuana use for the treatment of the most common medical and psychological conditions for which it has been allowed at the state level. Common medical conditions for which marijuana is allowed (i.e., those conditions shared by at least 80 percent of medical marijuana states) were identified as: Alzheimer's disease, amyotrophic lateral sclerosis, cachexia/wasting syndrome, cancer, Crohn's disease, epilepsy and seizures, glaucoma, hepatitis C virus, human immunodefici...
Source: Addiction Science and Clinical Practice - Category: Addiction Authors: Tags: Addict Sci Clin Pract Source Type: research
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