Meta-analytic evaluation of the association between head injury and risk of amyotrophic lateral sclerosis - Watanabe Y, Watanabe T.

Head injury is considered as a potential risk factor for amyotrophic lateral sclerosis (ALS). However, several recent studies have suggested that head injury is not a cause, but a consequence of latent ALS. We aimed to evaluate such a possibility of revers...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

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Conditions:   Stress Disorders, Post-Traumatic;   Trauma and Stressor Related Disorders;   Behavioral Symptoms;   Depression;   Quality of Life Interventions:   Behavioral: Body therapy;   Behavioral: Treatment as usual Sponsors:   University of Southern Denmark;   Danish Health Authority;   Soldaterlegatet;   The ManuVision Organization;   Military Psychiatric Center at Copenhagen University Hospital;   Patient Organization Denmark Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Post Traumatic Stress Disorder Interventions:   Behavioral: Service Dog Training Program;   Other: Dog Training Education Sponsor:   University of Maryland Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
The prevalence data presented in this report aims to further our understanding of the epidemiology of ALS cases in the United States.Morbidity &Mortality Weekly Report
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news
Amyotrophic Lateral Sclerosis (ALS) is a rapid progressive neurodegenerative disease, characterized by a selective loss of motor neurons, brain stem and spinal cord which leads to deterioration of motor abilit...
Source: BMC Neurology - Category: Neurology Authors: Tags: Research article Source Type: research
Bicondylar tibial plateau fractures are normally characterized by knee instability, pain, limited joint mobility, early post-traumatic osteoarthritis and are particularly difficult to treat successfully [1 –3]. Surgery is considered to be a definitive treatment option as it can provide anatomical reduction, sufficient stabilization, early mobilization, and, subsequently, an optimal functional outcome [4]. Routine diagnostic imaging, including x-ray, magnetic resonance (MR), computed tomography (CT), play a major role in the surgical management of plateau fractures.
Source: Injury - Category: Orthopaedics Authors: Source Type: research
Although joint injury itself damages joint tissues, a substantial amount of secondary damage is mediated by the cellular responses to the injury. Cellular responses include the production and activation of proteases (MMPs, ADAMTSs, Cathepsins), and the production of inflammatory cytokines. The trajectory of cellular responses is driven by the transcriptional activation of early response genes, which requires Cdk9-dependent RNA Polymerase II phosphorylation. Our objective was to determine whether inhibition of cdk9-dependent early response gene activation affects changes in the joint metabolome.
Source: Osteoarthritis and Cartilage - Category: Rheumatology Authors: Source Type: research
CONCLUSIONS: The data of this post-marketing study meet the request by the French authorities for additional data on conditions of use in everyday practice. They confirmed the tolerance and long-term effect of capsaicin 8% patch in patients with peripheral neuropathic pain in real-world conditions. PMID: 30550354 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
Publication date: Available online 15 December 2018Source: The Lancet NeurologyAuthor(s): Ralf Reilmann, Andrew McGarry, Igor D Grachev, Juha-Matti Savola, Beth Borowsky, Eli Eyal, Nicholas Gross, Douglas Langbehn, Robin Schubert, Anna Teige Wickenberg, Spyros Papapetropoulos, Michael Hayden, Ferdinando Squitieri, Karl Kieburtz, G Bernhard Landwehrmeyer, European Huntington's Disease Network, Pinky Agarwal, Karen E Anderson, Nasir A Aziz, Jean-Phillippe Azulay, Anne C Bachoud-LeviSummaryBackgroundPrevious trials have shown that pridopidine might reduce motor impairment in patients with Huntington's disease. The aim of this...
Source: The Lancet Neurology - Category: Neurology Source Type: research
CONCLUSIONS: Real acupuncture, compared with a sham needling procedure, resulted in a significant improvement in sleep measures for veterans with mTBI and disturbed sleep, even in the presence of PTSD. These results indicate that an alternative-medicine treatment modality like acupuncture can provide clinically significant relief for a particularly recalcitrant problem affecting large segments of the veteran population. TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT01162317. PMID: 30549498 [PubMed - in process]
Source: Journal of Clinical Psychiatry - Category: Psychiatry Tags: J Clin Psychiatry Source Type: research
A cross-sectional survey was conducted to collect primary data prospectively on pre-hospital care time intervals of Road Traffic Crash (RTC) victims that had been rescued by the Uganda police and to determine what factors were related to those intervals. T...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
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