Complementary and alternative medicine in Brazilian children and adolescents with type 1 diabetes mellitus.
CONCLUSIONS: The construction of the profile revealed a group of patients that deserve a special attention by health professionals because they are more prone to adopt behaviors that impair the success of the treatment, such as not counting carbohydrates and not informing the doctor about the use of CAM. PMID: 29073288 [PubMed - in process]
Conclusion: A novel control architecture for AP systems enables safe glycemic regulation with reduced processor computations. Significance: Our proposed framework integrated seamlessly with a wide variety of popular MPC variants reported in AP research, customizes tradeoff between glycemic regulation and efficacy according to prior design specifications, and eliminates judicious prior selection of controller sampling times.
This study assessed the relationship between Hb level and type 1 diabetic nephropathy (DN) in Anhui Han's patients. MethodsThere were a total of 236 patients diagnosed with type 1 diabetes mellitus and (T1DM) seen between January 2014 and December 2016 in our centre. Hemoglobin levels in patients with DN were compared with those without DN. The relationship between Hb level and the urinary albumin‐creatinine ratio (ACR) was examined by Spearman's correlational analysis and multiple stepwise regression analysis. The binary logistic multivariate regression analysis was performed to analyze the correlated factors for type 1...
Conclusions : GH may be diagnosed conservatively, based on corroborating medical history, physical examination, laboratory tests, imaging studies and response to treatment, even without liver biopsy. In case of doubt about the diagnosis or lack of clinical response to treatment, a liver biopsy may be considered. There is no role for noninvasive tests like fibroscan or fibrotest for the diagnosis of GH or for differentiation of this situation from nonalcoholic fatty liver disease.
Conclusions: Although subtle abnormalities of growth still persist, the modern advancements of insulin therapy are able to normalize puberty and final height of children with T1DM.Horm Res Paediatr
Condition: Type 1 Diabetes Mellitus Interventions: Drug: Insulin aspart SAR341402; Drug: Insulin aspart Sponsor: Sanofi Not yet recruiting
New treatments for type 1 diabetes are an unmet need. We investigated the efficacy and safety of adding SGLT‐2is to insulin for type 1 diabetes by meta‐analysis of prospective randomized, placebo‐controlled trials. Searching electronic databases up to October 2017 identified 1361 studies, among which 14 were investigated (N=4,591). Meta‐analysis revealed that SGLT‐2i therapy significantly reduced HbA1c by 0.4% (95% confidence interval [CI]: 0.35, 0.46; P
Conclusion This is a first report of ketonuria in a MS-patient with T1D treated with DMF. Patients with MS and co-existing metabolic diseases, which are not contraindicated for DMF treatment, represent a unique opportunity to address questions regarding the possible mechanisms of action of DMF on the cellular metabolism. The use of DMF in patients with metabolic diseases needs closer attention.
Authors: Nassiri Mansour R, Barati G, Soleimani M, Ghoraeian P, Nouri Aleagha M, Kehtari M, Mahboudi H, Hosseini F, Hassannia H, Abazari MF, Enderami SE Abstract Transplantation of islet is a promising method in treatment of patients with type 1 diabetes mellitus (T1DM), however, is limited by islet shortage. The aim of this study was to prepare a polyethersulfone (PES) nanofibrous scaffolds to evaluate the pancreatic differentiation of human induced pluripotent stem cells (hiPSCs). The differentiation process in tissue culture dishes and PES scaffolds was evaluated at mRNA and protein level by RT-qPCR and immunofl...
Journal Name: Journal of Pediatric Endocrinology and Metabolism Issue: Ahead of print
CONCLUSIONS: A diabetes educational program targeting high-risk population groups may reduce the prevalence of DKA nationwide. PMID: 29431304 [PubMed - in process]