Rapid Cocaine-Induced Spine Changes in the Nucleus Accumbens

In this issue of Biological Psychiatry, Dos Santos et  al. (1) use sophisticated new technologies to observe rapid and long-lasting cocaine-induced alterations of dendritic spines on medium spiny neurons (MSNs) in the nucleus accumbens (NAc), a brain region important for cocaine’s rewarding effects, and identify key signaling proteins that promote a nd maintain dendritic spine structural plasticity.

Source: Biological Psychiatry - October 28, 2017 Category: Psychiatry Authors: Rajtarun Madangopal Tags: Early Career Investigator Commentary Source Type: research