Application of an in vitro digestion model for 210 Po bioaccessibility assessment in seafood
This study aims to investigate the bioaccessibility of 210 Po in seafood and the impact of food
preparation on this radionuclide. Polonium bioaccessibility is the fraction of 210 Po mobilised from
food matrices into digestive extractants when applying an in vitro digestion model. The degree of
bioaccessibility of 210 Po in food has important implications for estimating ingestion doses from
this radionuclide. The simulation of gastrointestinal digestion was divided into three stages
through the use of synthetic saliva, gastric and bile –pancreas solutions. Following pre-treatment
with a saliva solution, raw and cooked seafood samples underwent one of the following treatments:
(a) simulated gastric digestion only or (b) simulated complete gastrointestinal digestion (gastric
digestion followed by bile-pancreas digestion). No significant difference ( P > 0.05) in 210 Po
mobility was found between samples that underwent gastric d...
Source: Journal of Radiological Protection - Category: Physics Authors: Carla Roselli, Donatella Desideri, Laura Feduzi, Lucia Ugolini and Maria Assunta Meli Source Type: research