Oligodendroglia-lineage cells in brain plasticity, homeostasis and psychiatric disorders.

Oligodendroglia-lineage cells in brain plasticity, homeostasis and psychiatric disorders.
Curr Opin Neurobiol. 2017 Oct 23;47:93-103
Authors: Birey F, Kokkosis AG, Aguirre A
Abstract
Adult oligodendrocyte progenitor cells are uniformly distributed in both gray and white matter, displaying robust proliferative and migratory potential during health and disease. Recently, developments in new experimental approaches have brought about several novel insights about NG2-glia and myelinating oligodendrocytes, indicating a diverse toolkit of functions in experience-dependent myelination and homeostasis in the adult CNS. In this review, we summarize some of the topical studies that highlight newly emerging findings implicating oligodendroglia-lineage cells in brain plasticity, homeostasis and pathophysiology of neuropsychiatric disorders.
PMID: 29073529 [PubMed - as supplied by publisher]

Source: Current Opinion in Neurobiology - October 23, 2017 Category: Neurology Authors: Birey F, Kokkosis AG, Aguirre A Tags: Curr Opin Neurobiol Source Type: research