Determination of the median effective dose (ED50) of bupivacaine and ropivacaine unilateral spinal anesthesia : Prospective, double blinded, randomized dose-response trial.

CONCLUSION: We find the ED50 were lower, and the ED50 of 0.5% hypobaric bupivacaine and ropivacaine was 4.66 mg (95% CI 4.69-4.63 mg) and 6.43 mg (95% CI 6.47-6.39 mg), respectively, for USpA in geriatric patients (age ≥ 70 years) undergoing elective hip replacement surgery. PMID: 29071370 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29071370?dopt=Abstract

Source: Der Anaesthesist - October 25, 2017 Category: Anesthesiology Authors: Wang W, Li Y, Sun A, Yu H, Dong J, Xu H Tags: Anaesthesist Source Type: research

More News: Anesthesia | Anesthesiology | Geriatrics | Study