Early Disseminated Lyme Disease Masquerading as Mononucleosis: A Case Report
Disseminated Lyme disease can be difficult to diagnose, as it begins with nonspecific signs and symptoms, which, if not treated correctly, can lead to atrioventricular conduction blocks and meningitis. In addition, the diagnosis can be further complicated by potentially false-positive test results.
Publication date: Available online 1 August 2020Source: Annals of Emergency MedicineAuthor(s): Hannah Holm Vestergaard, Lykke Larsen, Christian Brandt, Birgitte R. Hansen, Christian Ø. Andersen, Hans R. Lüttichau, Jannik Helweg-Larsen, Lothar Wiese, Merete Storgaard, Henrik Nielsen, Jacob Bodilsen
ConclusionListeria is difficult to isolate and it is not susceptible to first-line treatment for bacterial meningitis with extended-spectrum cephalosporins. Early recognition is therefore crucial for a positive outcome. Pediatricians have to perform close clinical monitoring of these children and be aware of possible complications.A review of all cases of Listeria meningitis complicated by hydrocephalus in healthy children has been performed, to provide an overview on clinical features, treatment options and outcome.
SATURDAY, Aug. 1, 2020 -- Summer means higher odds of getting Lyme disease, so know how to avoid it, health experts say. Lyme disease is caused by a bacterium carried by some ticks and, if left untreated, can cause severe health problems. Ticks can...
Meningitis and encephalitis (ME) are important causes of morbidity and mortality worldwide. Patients suspected of having ME are often hospitalized and started on empiric antimicrobial treatment, because of the potential adverse consequences of delaying the diagnosis or treatment. Multiplexed polymerase chain reaction panels are one of several rapid diagnostic technologies that have the potential to overcome some of the limitations of conventional diagnostic methods for ME. The BioFire FilmArray Meningitis/Encephalitis Panel was the first Food and Drug Administration–cleared multiplex polymerase chain reaction for the...
No abstract available
This study aimed to evaluate the imaging findings and prognostic factors after whole-brain radiotherapy in patients with carcinomatous meningitis from breast cancer. A retrospective analysis of imaging data and prognostic factors was performed in patients treated with whole-brain radiotherapy or whole-brain/spine radiotherapy immediately after the first diagnosis of carcinomatous meningitis from breast cancer at our hospital from January 1, 2010 to December 31, 2018. Statistical significance was set at P
Lyme disease is the most prevalent vector-borne disease in the USA with cases continuing to increase. Current control measures have not been shown to be impactful, and therefore alternatives are needed. Treati...
Invasive meningococcal disease (IMD) is a serious condition caused by Neisseria meningitidis. The incidence of IMD fluctuates considerably from one region to another and over time, while remaining relatively low worldwide. In the last two decades, 0.01 to 3.6 cases/100,000 persons were estimated globally . IMD incidence is the highest in infants, and a second, lower peak is observed in adolescents , which is also the age group with the highest meningococcal carriage rates . IMD can be a deadly disease if untreated and is associated with high case-fatality rates of 4.1% to 20.0%, even with prompt treatment .
A vaccine against Lyme disease that is safe and stimulated immune protection in 82 to 96 per cent of clinical trial participants could be available by 2025
A female infant underwent myelomeningocele repair and developed persistent ventricular dilatation. Cerebrospinal fluid (CSF) indices demonstrated meningitis with cultures growing Mycoplasma hominis. The infant was treated with multiple antibiotics including moxifloxacin. Moxifloxacin CSF levels were obtained for pharmacokinetic analysis. This case report adds the importance of understanding the pharmacokinetics of CSF moxifloxacin levels among infants.