Cognitive Outcome after Epilepsy Surgery in Children

Cognitive dysfunction in children with epilepsy is primarily contributed by etiology, seizures, frequency of inter-ictal epileptiform discharges, and adverse effects of anti-epileptic drugs. The direct impact of epilepsy surgery on cognitive outcome depends on 2 key factors: the function that is present in the epileptogenic zone to be removed, and the dysfunction outside the epileptogenic zone caused by epilepsy. Studies on cognitive outcome in children after various types of epilepsy surgery estimate ‘no significant change′ in about 70% of children, improvement in cognition in 10–15%, and decline in 10–15%.
Source: Seminars in Pediatric Neurology - Category: Neurology Authors: Source Type: research