Diffuse-Type Hepatoma: A Grave Prognostic Marker

This study was planned to compare nodular- and diffuse-type HCC in this cohort.Methods: CT scans of 227 patients with HCC negative for infective hepatitis were analyzed and grouped as nodular and diffuse from July 2011 to July 2014. Diffuse-type cancer was defined as a tumor without convex/distinct margin, diffusely infiltrating the hepatic parenchyma. There were 45 (20%) cases. The baseline liver functions, etiology, treatment, and the outcome were compared with nodular-type cancers. Stage III diffuse cancers were matched with 2 stage III nodular cancers looking at the T stage and background liver.Results: There was no difference in the age (63 vs. 62 years,p = 0.937) and gender. Diffuse cancers had a low BMI (24 vs. 22,p = 0.009), a higher alpha fetoprotein (AFP) level (p
Source: Gastrointestinal Tumors - Category: Gastroenterology Source Type: research