UT Health San Antonio researchers define mechanism that causes kidney cancer to recur

(University of Texas Health Science Center at San Antonio) Researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) and US Department of Veterans Affairs have identified the molecular mechanism causing kidney cancer to resist drug treatment. The findings were published in the journal Nature Communications. They discovered NOX4, an enzyme in the cell's mitochondria, senses the Warburg effect (movement of adenosine triphosphate's energy production from inside to outside the mitochondria), and switches on to initiate drug resistance.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news