Diagnosis of multiple system atrophy
Multiple system atrophy (MSA) may be difficult to distinguish clinically from other disorders, particularly in the early stages of the disease. An autonomic-only presentation can be indistinguishable from pure autonomic failure. Patients presenting with Parkinsonism may be misdiagnosed as having Parkinson disease. Patients presenting with the cerebellar phenotype of MSA can mimic other adult-onset ataxias due to alcohol, chemotherapeutic agents, lead, lithium, and toluene, or vitamin E deficiency, as well as paraneoplastic, autoimmune, or genetic ataxias.
Source: Autonomic Neuroscience: Basic and Clinical - Category: Neuroscience Authors: Jose-Alberto Palma, Lucy Norcliffe-Kaufmann, Horacio Kaufmann Tags: Review Source Type: research
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