COL4A2 is associated with lacunar ischemic stroke and deep ICH: Meta-analyses among 21,500 cases and 40,600 controls

Conclusions:
These results provide evidence of shared genetic determinants and suggest common pathophysiologic mechanisms of distinct ischemic and hemorrhagic cerebral SVD stroke phenotypes, offering new insights into the causal mechanisms of cerebral SVD.

Source: Neurology - October 23, 2017 Category: Neurology Authors: Rannikmäe, K., Sivakumaran, V., Millar, H., Malik, R., Anderson, C. D., Chong, M., Dave, T., Falcone, G. J., Fernandez-Cadenas, I., Jimenez-Conde, J., Lindgren, A., Montaner, J., O'Donnell, M., Pare, G., Radmanesh, F., Rost, N. S., Slowik, A., So& Tags: All Cerebrovascular disease/Stroke, Infarction, Intracerebral hemorrhage, All Genetics, Association studies in genetics ARTICLE Source Type: research