Penn study links mutations in notch gene to role in B cell cancers

(University of Pennsylvania School of Medicine) Researchers found that in B cell tumors, mutated overactive versions of the Notch protein directly drive the expression of the Myc gene and many other genes that participate in B cell signaling pathways. Myc is a critical gene in governing cell proliferation and survival.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news