B3 vitamin component fights carcinogen action in human cells, says research

(Funda ç ã o de Amparo à Pesquisa do Estado de S ã o Paulo) Brazilian scientists investigate tumoral development caused by benzo[a]pyrene, a hydrocarbon present in cigarette smoke, automotive exhaust, burnt wood fumes and barbecued meat. Culture of human lung cells was exposed to the agent for a week; the preventive role of nicotinamide riboside halted the damaging effects derived from alterations in genetic expression and cell metabolism.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news

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Are you a mom struggling with loads of self-doubt? Just know you’re not alone. Today’s guest, Katherine Wintsch, author and researcher of modern motherhood, discusses the “dragon of self-doubt” that many moms grapple with. This doubt can manifest as comparing ourselves to other moms, imagining a doomsday future or just sheer exhaustion. Do you struggle to feel “good enough” as a parent or a partner? Do you feel desperate to get that next job promotion? Do you call yourself “fat” or a host of other ugly names? Tune in for real strategies to overcome these self-doubt dragons. ...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Children and Teens General Inspiration & Hope Interview LifeHelper Parenting Podcast The Psych Central Show Source Type: blogs
It was a great honor to receive hundreds of questions before the live Q&A we recently had. There were in fact so many that I’ve decided I would share some of them here. These questions represent an ample mix of interests, covering a wide range of issues from A.I. to the future of medical education. And worry not if you haven’t gotten your question answered just yet: in the coming weeks we’ll also be writing articles that are based on some of the most intriguing questions. Re-watch the event on YouTube: #1 On The Relationship Of Doctors And Patients What sort of strategies can we use...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: 3D Printing Artificial Intelligence Digital Health Research E-Patients Future of Medicine Future of Pharma Healthcare Design Robotics Security & Privacy Telemedicine & Smartphones AI Hospital Medical education technology wearab Source Type: blogs
Contributors : Hale Tunbak ; Rocio Enriquez-Gasca ; Christopher H Tie ; Poppy A Gould ; Petra Mlcochova ; Ravi Gupta ; Liane Fernandes ; James Holt ; Annemarthe G van der Veen ; Evangelos Giampazolias ; Kathleen H Burns ; Pierre V Maillard ; Helen M RoweSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe Human Silencing Hub (HUSH) complex is necessary for epigenetic repression of LINE-1 elements. We found that depletion of HUSH components in human cell lines and primary fibroblasts leads to induction of interferon-stimulated genes (ISGs) through JAK/STAT signaling. This effect was mai...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
As the world watched in horror the brutal murder of George Floyd by a police officer, many people are searching for answers. In today’s Psych Central Podcast, Gabe and Okpara Rice, MSW, tackle all of the tough subjects: white privilege, systemic racism, disparities in education and the concept behind Black Lives Matter. Why does racism still exist in America and what can be done? Tune in for an informative discussion on race that leaves no stone unturned. This podcast was originally a live recording on Facebook. SUBSCRIBE &REVIEW   Guest information for ‘Okpara Rice- Racism Trauma’ Podcast ...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Interview Podcast Policy and Advocacy Racism The Psych Central Show Source Type: blogs
Muscle cachexia is a catabolic response, usually takes place in various fatal diseases, such as sepsis, burn injury, and chronic kidney disease. Muscle cachexia is also a common co-morbidity seen in the vast majority of advanced cancer patients, often associated with low quality of life and death due to general organ dysfunction. The triggering events and underlying molecular mechanisms of muscle wasting are not yet clearly defined. Our recent study has shown that the ectopic expression of Twist1 in muscle progenitor cells is sufficient to drive muscle structural protein breakdown and attendant muscle atrophy, reminiscent ...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
CONCLUSIONS: Vitamin D concerns related to sunscreen use remained common among Australian adults. Skin cancer control advocates may be reassured that those with greatest skin cancer risk (burn only) were less likely to hold these concerns, while the related infrequent sun protection and tanning among concerned adults is problematic. So what? Continued education and research is needed to ensure that the general public understand the risks and benefits of sun exposure in Australia. PMID: 32557897 [PubMed - as supplied by publisher]
Source: Health Promotion Journal of Australia - Category: International Medicine & Public Health Tags: Health Promot J Austr Source Type: research
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Xeroderma pigmentosum (XP) is a rare autosomal recessive disease of DNA repair characterized by severe ultraviolet (UV) sensitivity resulting in a 10,000-fold increased risk for skin cancer. Symptoms include freckle-like pigmentation in sun exposed skin before age 2 years, severe burns after minimal sun exposure (50% of patients) and skin cancers in children. XP is also considered a premature aging disease because of its features such as: dry skin, increased sun-induced freckling in young patients, higher incidence of skin cancers in young patients and premature menopause.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Carcinogenesis and Cancer Genetics Source Type: research
7:39 a.m. That’s the time that your smartphone’s sonar deems as optimal for you to wake up today. With its gentle vibration from your bedside table, you pick it up to turn off the smart alarm. As you do so, your phone asks for your permission to use the built-in sensors and camera to run your routine morning scan. It analyzes your voice; evaluates your stress level based on a facial scan; checks your vital signs; and notifies you to take a picture of that mole on your forearm in order to detect any anomalies.  Thereafter, it outputs a comprehensible report with recommendations which you can send over to...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Artificial Intelligence E-Patients Health Sensors & Trackers Telemedicine & Smartphones stress health trackers Huntington's Alzheimer's disease covid19 camera apple health google fit WHO hemoglobin SpO2 Samsung oximetry F Source Type: blogs
AbstractBackgroundData regarding prolonged length of hospital stay (PLOS) and in-hospital mortality are paramount to evaluate efficiency and quality of surgical care as well as for rational resource utilization, allocation, and administration. Thus, PLOS and in-hospital mortality have been used as a surrogate indicator of satisfactory treatment outcome and efficient utilization of resources for a given health institution. However, there was a scarcity of data regarding these issues in Ethiopia. Therefore, this study aimed to assess treatment outcome, length of hospital stay, in-hospital mortality, and their determinants.Me...
Source: Journal of Pharmaceutical Policy and Practice - Category: Pharmaceuticals Source Type: research
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