Nanotechnology and Adeno-associated virus based decorin gene therapy ameliorates Peritoneal Fibrosis.

Conclusion: This study shows that both GNP-delivered and AAV-mediated decorin gene therapies significantly decrease peritoneal fibrosis in vivo in rodent model. This approach has important clinical translational potential in providing a therapeutic strategy to prevent peritoneal fibrosis in PD patients. PMID: 25056353 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/25056353?dopt=Abstract

Source: Am J Physiol Renal P... - July 23, 2014 Category: Urology & Nephrology Authors: Chaudhary K, Moore H, Tandon A, Gupta S, Khanna R, Mohan RR Tags: Am J Physiol Renal Physiol Source Type: research