Lung toxicity after radiation in childhood: Results of the International Project on Prospective Analysis of Radiotoxicity in Childhood and Adolescence.

CONCLUSION: Acute and late toxicities appear to be correlated with higher irradiation volumes and low doses. Our data indicate that similar to the situation in adult patients, V5, V10, V15 and V20 should be kept as low as possible (e.g., at least V5 < 50%, V10 and V15 < 35% and V20 < 30%) in children and adolescents to lower the risk of toxicity.
PMID: 29050956 [PubMed - as supplied by publisher]

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - October 16, 2017 Category: Radiology Authors: Stoppel G, Eich HT, Matuschek C, Kortmann RD, Meyer F, Martinsson U, Nilsson K, Kristensen I, Vordermark D, Willich N, Christiansen H, Koch R, Steinmann D Tags: Radiother Oncol Source Type: research