Circulating levels of proinflammatory mediators as potential biomarkers of post-traumatic knee osteoarthritis development

ConclusionsCirculating NOx level and a combination of IL-6 and leptin permitted the strongest discrimination of patients with PTOA from controls. PTOA severity was correlated with leptin levels in plasma and SF and with the synovial IL-18 level. Early PTOA was associated with the circulating level of IL-1 β.Level of evidenceIII (case –control study).
Source: Journal of Orthopaedics and Traumatology - Category: Orthopaedics Source Type: research