Ultrasound functional imaging in an ex vivo beating porcine heart platform.

In this study, an isolated beating pig heart setup was adapted and used for performance assessment of UFI techniques such as volume assessment and ultrasound strain imaging. The potential of performing verification and reproducibility studies was demonstrated. For proof-of-principle, validation of UFI in pathological hearts was examined. Ex vivo porcine hearts (n = 6, slaughterhouse waste) were resuscitated and attached to a mock circulatory system. Radio frequencyt ultrasound data of the left ventricle were acquired in five short axis views and one long axis view. Based on these slices, the cardiac outputCO was measured, where verification was performed using flow sensor measurements in the aorta. strain Strain imaging was performed providing radial, circumferential and longitudinal strain to assess reproducibility and inter-subject variability under steady conditions. Finally, strains in healthy hearts were compared to a heart with an implanted left ventricular assist device, simulating a failing, supported heart. Good agreement between US and flow sensor based CO measurements was found. Strains were highly reproducible (intraclass correlation coefficients > 0.8). Differences were found due to biological variation and condition of the hearts. Strain magnitude and patterns in the assisted heart were available for different pump action, revealing large changes compared to the normal condition. The setup provides a valuable benchmarking platform for UFI technique...
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research

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Publication date: Available online 17 September 2019Source: Trends in Food Science &TechnologyAuthor(s): Swati Mahato, Zhiwei Zhu, Da-Wen SunAbstractBackgroundStability of food is a great challenge that encompasses the interaction among the constituents, processing conditions and thermal history. The frozen storage of food sometimes incurs possible harmful effect due to the formation of large ice crystal and destruction of the cell structure. Glass transition state is a second-order transition of matter where a system reaches a thermodynamically non-equilibrium state due to the immobility of molecules, and it is a univ...
Source: Trends in Food Science and Technology - Category: Food Science Source Type: research
Publication date: January 2020Source: LWT, Volume 117Author(s): Chang-Cheng Zhao, Pyo-Hyeon Kim, Jong-Bang EunAbstractThe aim of this study was to evaluate the influences of ultrasound treatment on the color attributes, total protein, total phenol and flavonoid content, isoflavone composition (genistin, daidzin, glycitin, genistein, daidzein, and glycitein), and antioxidant activity of tofu whey. Fourier transform infrared assay was performed and the microstructure of treated tofu whey was evaluated. The results showed ultrasound application significantly increased the total phenolic and flavonoid content, isoflavone gluco...
Source: LWT Food Science and Technology - Category: Food Science Source Type: research
ConclusionsThe incidence of VTE complications after endovenous laser ablation was low. Furthermore, the value of performing postoperative ultrasound for VTE management seems to be low because the occurrence of severe VTE complications could not be predicted by lower extremity venous ultrasound. Although the perioperative detection of VTE complications by this modality resulted in the early administration of anticoagulant therapy and may have contributed to improved prognosis, the number of those patients was limited.
Source: Journal of Vascular Surgery: Venous and Lymphatic Disorders - Category: Surgery Source Type: research
Healthcare systems are often compared with the aviation industry. Progress in both is highly desired but must always be achieved with safety in mind. Everyone wants to get from point A to point B faster and more comfortably, but how much risk of uncertainty is one ready to accept to achieve that extra speed? Both industries also share the aspect of competition for customers. In the field of localized prostate cancer, patients have an ever-increasing choice of options: radical surgery (open vs laparoscopic vs robot-assisted), external beam radiation therapy (EBRT) (with photons or protons), brachytherapy (low-dose rate or h...
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Clinical Investigation Source Type: research
Conclusions: Lung ultrasound may help highlight pulmonary gangrene, a poorly-known disease, with this new ultrasonographic description. The next step will be to ascertain the relation between this new ultrasound feature and pulmonary gangrene and to assess how this bedside diagnosis could impact the prognosis of the disease.
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Online Case Report Source Type: research
Publication date: Available online 16 September 2019Source: Sensors and Actuators A: PhysicalAuthor(s): Hojong ChoiAbstractCompared with low-frequency (≤15 MHz) ultrasonic transducers, high-frequency ultrasonic transducers provide higher spatial resolutions while reducing the echo-signal amplitudes and bandwidths owing to the size reduction of the piezoelectric materials. Therefore, performance improvement of high-frequency ultrasonic transducers can enhance the performance of the whole ultrasound instrument. To improve the echo-signal quality, such as the amplitudes, signal distortions, and bandwidths, negative-group-d...
Source: Sensors and Actuators A: Physical - Category: Physics Source Type: research
In this paper, we demonstrate 1-kHz-repetition-rate laser ultrasound in carbon-fiber-reinforced plastics (CFRPs). A ZGP master oscillator ...
Source: Applied Optics - Category: Physics Authors: Source Type: research
In this study, we developed an ultrasound-assisted fractional precipitation for the purification of poorly water-soluble anticancer agent paclitaxel. The effects of ultrasound power (80, 180, 250, and 380 W) were investigated in samples of different purity (20.4, 63.6, and 92.7%) for precipitation. Higher precipitation rate and shorter precipitation time were found with ultrasound treated solutions than with those without ultrasound. When the experimental data were applied to the Johnson-Mehl-Avrami-Komolgorov (JMAK) equation, the rate constant increased to 200-500-fold for 20.4% of sample purity, 150-250-fold for 6...
Source: Process Biochemistry - Category: Biochemistry Source Type: research
Conclusions Uterus-preserving LLSM (abdominocervicopexy) was found to be effective for the correction of apical and anterior prolapse with high levels of patient satisfaction. Significant improvements in urge symptoms and frequency of nocturia were observed. Pelvic floor ultrasound outcomes may be useful when comparing this procedure with other surgical techniques. PMID: 31523099 [PubMed]
Source: Geburtshilfe und Frauenheilkunde - Category: OBGYN Tags: Geburtshilfe Frauenheilkd Source Type: research
Conclusions: The MRI-TRUS image fusion is a feasible tool for the visualization of the prostate gland, particularly at the apex and base of the gland. Tumor identification presents the potential for dose escalation using fusion, especially for anteriorly located tumors. PMID: 31523238 [PubMed]
Source: Journal of Contemporary Brachytherapy - Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
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